Advanced computational analysis of CD40LG variants in atypical X-linked hyper-IgM syndrome

Keyphrases

• Computational Analysis 100%
• Hyper-IgE Syndrome 100%
• CD40LG 100%
• CD40 Ligand (CD40L) 50%
• Molecular Dynamics Simulation 25%
• Clinical Features 25%
• Protein Expression 25%
• Protein Binding 25%
• Flow Cytometry 25%
• CD40 25%
• Deleterious Effects 25%
• Pathogenic Variants 25%
• Structural Alterations 25%
• Clinical Setting 25%
• Variants of Uncertain Significance 25%
• Functional Analysis 25%
• Protein S Deficiency 25%
• Binding Capacity 25%
• Molecular Mechanics Calculations 25%
• Immunological Characteristics 25%
• Protein Motion 25%

Biochemistry, Genetics and Molecular Biology

• Immunoglobulin M 100%
• Wild Type 50%
• Protein Expression 50%
• Binding Protein 50%
• Molecular Mechanic 50%
• Movement Proteins 50%
• Flow Cytometry 50%