Adult Cancer Pain, Version 2.2025

Robert A. Swarm; Jeanie M. Youngwerth; Julia L. Agne; Magdalena Anitescu; Madhuri Are; Sorin Buga; Taylor Butler; Marcin Chwistek; James Cleary; David Copenhaver; Christopher Coyne; David Craig; Heidi Finnes; Heather Greenlee; Mona Gupta; Eric Hansen; Saba Javed; Enas Kandil; Sean Mackey; Andrew McDonald; Kathryn McGrath; Natalie Moryl; Suzanne Nesbit; Michael Noonan; Joseph Norris; Judith A. Paice; Elizabeth Prsic; Michael W. Rabow; Elizabeth Rickerson; Jill Sindt; Michael Smith; Kevin Vorenkamp; Justine Yang Bruce; Sun Yoo; Rebecca Cunningham; Lisa A. Gurski; Frankie Jones

doi:10.6004/jnccn.2025.0032

Adult Cancer Pain, Version 2.2025

Robert A. Swarm
, Jeanie M. Youngwerth
, Julia L. Agne
, Magdalena Anitescu
, Madhuri Are
, Sorin Buga
, Taylor Butler
, Marcin Chwistek
, James Cleary
, David Copenhaver
, Christopher Coyne
, David Craig
, Heidi Finnes
, Heather Greenlee
, Mona Gupta
, Eric Hansen
, Saba Javed
, Enas Kandil
, Sean Mackey
, Andrew McDonald

Kathryn McGrath, Natalie Moryl, Suzanne Nesbit, Michael Noonan, Joseph Norris, Judith A. Paice, Elizabeth Prsic, Michael W. Rabow, Elizabeth Rickerson, Jill Sindt, Michael Smith, Kevin Vorenkamp, Justine Yang Bruce, Sun Yoo, Rebecca Cunningham, Lisa A. Gurski, Frankie Jones

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Adult Cancer Pain provide recommendations for the comprehensive management of pain in patients with cancer. This article will focus on methods for screening for pain, safe and appropriate prescription of opioid and miscellaneous analgesics, and the optimization of nonpharmacologic interventions including integrative and interventional strategies for treatment of cancer-related pain. Additionally, the NCCN Guidelines discuss methods for the safe reduction of opioids when appropriate, as well as techniques for encouraging the judicious use of opioids. The complete version of the NCCN Guidelines for Adult Cancer Pain addresses additional issues that are not covered here, including management of pain during a pain crisis, management of procedure-related pain and anxiety, pain management for cancer survivors, and the use of nonopioid and adjuvant analgesics for cancer-related pain.

Original language	English
Article number	e250032
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	23
Issue number	7
DOIs	https://doi.org/10.6004/jnccn.2025.0032
State	Published - Jul 2025

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Swarm, R. A., Youngwerth, J. M., Agne, J. L., Anitescu, M., Are, M., Buga, S., Butler, T., Chwistek, M., Cleary, J., Copenhaver, D., Coyne, C., Craig, D., Finnes, H., Greenlee, H., Gupta, M., Hansen, E., Javed, S., Kandil, E., Mackey, S., ... Jones, F. (2025). Adult Cancer Pain, Version 2.2025. JNCCN Journal of the National Comprehensive Cancer Network, 23(7), Article e250032. https://doi.org/10.6004/jnccn.2025.0032

@article{158a1833ffd34951a9a3a52eb5a407dd,

title = "Adult Cancer Pain, Version 2.2025",

abstract = "The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Adult Cancer Pain provide recommendations for the comprehensive management of pain in patients with cancer. This article will focus on methods for screening for pain, safe and appropriate prescription of opioid and miscellaneous analgesics, and the optimization of nonpharmacologic interventions including integrative and interventional strategies for treatment of cancer-related pain. Additionally, the NCCN Guidelines discuss methods for the safe reduction of opioids when appropriate, as well as techniques for encouraging the judicious use of opioids. The complete version of the NCCN Guidelines for Adult Cancer Pain addresses additional issues that are not covered here, including management of pain during a pain crisis, management of procedure-related pain and anxiety, pain management for cancer survivors, and the use of nonopioid and adjuvant analgesics for cancer-related pain.",

author = "Swarm, \{Robert A.\} and Youngwerth, \{Jeanie M.\} and Agne, \{Julia L.\} and Magdalena Anitescu and Madhuri Are and Sorin Buga and Taylor Butler and Marcin Chwistek and James Cleary and David Copenhaver and Christopher Coyne and David Craig and Heidi Finnes and Heather Greenlee and Mona Gupta and Eric Hansen and Saba Javed and Enas Kandil and Sean Mackey and Andrew McDonald and Kathryn McGrath and Natalie Moryl and Suzanne Nesbit and Michael Noonan and Joseph Norris and Paice, \{Judith A.\} and Elizabeth Prsic and Rabow, \{Michael W.\} and Elizabeth Rickerson and Jill Sindt and Michael Smith and Kevin Vorenkamp and Bruce, \{Justine Yang\} and Sun Yoo and Rebecca Cunningham and Gurski, \{Lisa A.\} and Frankie Jones",

year = "2025",

month = jul,

doi = "10.6004/jnccn.2025.0032",

language = "English",

volume = "23",

journal = "JNCCN Journal of the National Comprehensive Cancer Network",

issn = "1540-1405",

number = "7",

}

Swarm, RA, Youngwerth, JM, Agne, JL, Anitescu, M, Are, M, Buga, S, Butler, T, Chwistek, M, Cleary, J, Copenhaver, D, Coyne, C, Craig, D, Finnes, H, Greenlee, H, Gupta, M, Hansen, E, Javed, S, Kandil, E, Mackey, S, McDonald, A, McGrath, K, Moryl, N, Nesbit, S, Noonan, M, Norris, J, Paice, JA, Prsic, E, Rabow, MW, Rickerson, E, Sindt, J, Smith, M, Vorenkamp, K, Bruce, JY, Yoo, S, Cunningham, R, Gurski, LA & Jones, F 2025, 'Adult Cancer Pain, Version 2.2025', JNCCN Journal of the National Comprehensive Cancer Network, vol. 23, no. 7, e250032. https://doi.org/10.6004/jnccn.2025.0032

TY - JOUR

T1 - Adult Cancer Pain, Version 2.2025

AU - Swarm, Robert A.

AU - Youngwerth, Jeanie M.

AU - Agne, Julia L.

AU - Anitescu, Magdalena

AU - Are, Madhuri

AU - Buga, Sorin

AU - Butler, Taylor

AU - Chwistek, Marcin

AU - Cleary, James

AU - Copenhaver, David

AU - Coyne, Christopher

AU - Craig, David

AU - Finnes, Heidi

AU - Greenlee, Heather

AU - Gupta, Mona

AU - Hansen, Eric

AU - Javed, Saba

AU - Kandil, Enas

AU - Mackey, Sean

AU - McDonald, Andrew

AU - McGrath, Kathryn

AU - Moryl, Natalie

AU - Nesbit, Suzanne

AU - Noonan, Michael

AU - Norris, Joseph

AU - Paice, Judith A.

AU - Prsic, Elizabeth

AU - Rabow, Michael W.

AU - Rickerson, Elizabeth

AU - Sindt, Jill

AU - Smith, Michael

AU - Vorenkamp, Kevin

AU - Bruce, Justine Yang

AU - Yoo, Sun

AU - Cunningham, Rebecca

AU - Gurski, Lisa A.

AU - Jones, Frankie

PY - 2025/7

Y1 - 2025/7

N2 - The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Adult Cancer Pain provide recommendations for the comprehensive management of pain in patients with cancer. This article will focus on methods for screening for pain, safe and appropriate prescription of opioid and miscellaneous analgesics, and the optimization of nonpharmacologic interventions including integrative and interventional strategies for treatment of cancer-related pain. Additionally, the NCCN Guidelines discuss methods for the safe reduction of opioids when appropriate, as well as techniques for encouraging the judicious use of opioids. The complete version of the NCCN Guidelines for Adult Cancer Pain addresses additional issues that are not covered here, including management of pain during a pain crisis, management of procedure-related pain and anxiety, pain management for cancer survivors, and the use of nonopioid and adjuvant analgesics for cancer-related pain.

AB - The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Adult Cancer Pain provide recommendations for the comprehensive management of pain in patients with cancer. This article will focus on methods for screening for pain, safe and appropriate prescription of opioid and miscellaneous analgesics, and the optimization of nonpharmacologic interventions including integrative and interventional strategies for treatment of cancer-related pain. Additionally, the NCCN Guidelines discuss methods for the safe reduction of opioids when appropriate, as well as techniques for encouraging the judicious use of opioids. The complete version of the NCCN Guidelines for Adult Cancer Pain addresses additional issues that are not covered here, including management of pain during a pain crisis, management of procedure-related pain and anxiety, pain management for cancer survivors, and the use of nonopioid and adjuvant analgesics for cancer-related pain.

UR - https://www.scopus.com/pages/publications/105011135746

U2 - 10.6004/jnccn.2025.0032

DO - 10.6004/jnccn.2025.0032

M3 - Article

C2 - 40639401

AN - SCOPUS:105011135746

SN - 1540-1405

VL - 23

JO - JNCCN Journal of the National Comprehensive Cancer Network

JF - JNCCN Journal of the National Comprehensive Cancer Network

IS - 7

M1 - e250032

ER -

Adult Cancer Pain, Version 2.2025

Abstract

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