Adrenal vein sampling for ACTH-producing pheochromocytomas

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Adrenocorticotropic hormone (ACTH)-producing pheochromocytoma can cause a variety of clinical manifestations of excess catecholamine and corticosteroid. Anatomic localization of this source of ectopic ACTH is critical to facilitate unilateral adrenalectomy and prevent adrenal insufficiency due to bilateral adrenalectomy. Although nuclear scintigraphy remains the diagnostic gold standard, recent radiotracer supply shortages have necessitated alternative diagnostic paradigms to localize adrenal pheochromocytomas. We present a case where adrenal vein sampling (AVS) was utilized to lateralize an adrenal pheochromocytoma and discuss the approach and nuance as it differs from routine AVS for hyperaldosteronism or hypercortisolism.

Original languageEnglish
Pages (from-to)2672-2675
Number of pages4
JournalRadiology Case Reports
Issue number9
StatePublished - Sep 2021


  • ACTH-producing pheochromocytoma
  • Adrenal vein sampling
  • Pheochromocytoma
  • Venous intervention


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