TY - JOUR
T1 - Added Value of FDG PET/MRI in Gynecologic Oncology
T2 - A Pictorial Review
AU - Tarcha, Ziad
AU - Konstantinoff, Katerina S.
AU - Ince, Semra
AU - Fraum, Tyler J.
AU - Sadowski, Elizabeth A.
AU - Bhosale, Priya R.
AU - Derenoncourt, Paul Robert
AU - Zulfiqar, Maria
AU - Shetty, Anup S.
AU - Ponisio, Maria R.
AU - Mhlanga, Joyce C.
AU - Itani, Malak
N1 - Publisher Copyright:
© RSNA, 2023.
PY - 2023/8
Y1 - 2023/8
N2 - Fluorine 18–fluorodeoxyglucose (FDG) PET and MRI independently play a valu-able role in the management of patients with gynecologic malignancies, particularly endometrial and cervical cancer. The PET/MRI hybrid imaging technique combines the metabolic information obtained from PET with the excellent soft-tissue resolution and anatomic de-tails provided by MRI in a single exam-ination. MRI is the modality of choice for assessment of local tumor extent in the pelvis, whereas PET is used to assess for local-regional spread and distant metasta-ses. The authors discuss the added value of FDG PET/MRI in imaging gynecologic malignancies of the pelvis, with a focus on the role of FDG PET/MRI in diagno-sis, staging, assessing treatment response, and characterizing complications. PET/ MRI allows better localization and de-marcation of the extent of disease, characterization of lesions and involvement of adjacent organs and lymph nodes, and improved differentiation of benign from malignant tissues, as well as detection of the presence of distant metastasis. It also has the advantages of decreased radiation dose and a higher signal-to-noise ratio of a prolonged PET examination of the pelvis contemporaneous with MRI. The authors provide a brief technical overview of PET/MRI, highlight how simultaneously performed PET/MRI can improve stand-alone MRI and PET/CT in gynecologic malignancies, provide an image-rich review to illustrate practical and clinically relevant applications of this imaging technique, and review common pitfalls encountered in clinical practice.
AB - Fluorine 18–fluorodeoxyglucose (FDG) PET and MRI independently play a valu-able role in the management of patients with gynecologic malignancies, particularly endometrial and cervical cancer. The PET/MRI hybrid imaging technique combines the metabolic information obtained from PET with the excellent soft-tissue resolution and anatomic de-tails provided by MRI in a single exam-ination. MRI is the modality of choice for assessment of local tumor extent in the pelvis, whereas PET is used to assess for local-regional spread and distant metasta-ses. The authors discuss the added value of FDG PET/MRI in imaging gynecologic malignancies of the pelvis, with a focus on the role of FDG PET/MRI in diagno-sis, staging, assessing treatment response, and characterizing complications. PET/ MRI allows better localization and de-marcation of the extent of disease, characterization of lesions and involvement of adjacent organs and lymph nodes, and improved differentiation of benign from malignant tissues, as well as detection of the presence of distant metastasis. It also has the advantages of decreased radiation dose and a higher signal-to-noise ratio of a prolonged PET examination of the pelvis contemporaneous with MRI. The authors provide a brief technical overview of PET/MRI, highlight how simultaneously performed PET/MRI can improve stand-alone MRI and PET/CT in gynecologic malignancies, provide an image-rich review to illustrate practical and clinically relevant applications of this imaging technique, and review common pitfalls encountered in clinical practice.
UR - http://www.scopus.com/inward/record.url?scp=85164248530&partnerID=8YFLogxK
U2 - 10.1148/rg.230006
DO - 10.1148/rg.230006
M3 - Article
C2 - 37410624
AN - SCOPUS:85164248530
SN - 0271-5333
VL - 43
JO - Radiographics
JF - Radiographics
IS - 8
M1 - e230006
ER -