TY - JOUR
T1 - Adaptation
T2 - Paradigm for the gut and an academic career
AU - Warner, Brad W.
PY - 2013/1
Y1 - 2013/1
N2 - Adaptation is an important compensatory response to environmental cues resulting in enhanced survival. In the gut, the abrupt loss of intestinal length is characterized by increased rates of enterocyte proliferation and apoptosis and culminates in adaptive villus and crypt growth. In the development of an academic pediatric surgical career, adaptation is also an important compensatory response to survive the ever changing research, clinical, and economic environment. The ability to adapt in both situations is critical for patients and a legacy of pediatric surgical contributions to advance our knowledge of multiple conditions and diseases.
AB - Adaptation is an important compensatory response to environmental cues resulting in enhanced survival. In the gut, the abrupt loss of intestinal length is characterized by increased rates of enterocyte proliferation and apoptosis and culminates in adaptive villus and crypt growth. In the development of an academic pediatric surgical career, adaptation is also an important compensatory response to survive the ever changing research, clinical, and economic environment. The ability to adapt in both situations is critical for patients and a legacy of pediatric surgical contributions to advance our knowledge of multiple conditions and diseases.
KW - Intestinal adaptation
KW - Intestinal resection
KW - Pediatric surgery
KW - Short gut syndrome
KW - Surgical research
UR - http://www.scopus.com/inward/record.url?scp=84872399035&partnerID=8YFLogxK
U2 - 10.1016/j.jpedsurg.2012.10.014
DO - 10.1016/j.jpedsurg.2012.10.014
M3 - Review article
C2 - 23331788
AN - SCOPUS:84872399035
SN - 0022-3468
VL - 48
SP - 20
EP - 26
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 1
ER -