Acute Retinal Necrosis Syndrome Presenting with Papillitis and Arcuate Neuroretinitis

Todd Margolis, Alexander R. Irvine, William F. Hoyt, Richard Hyman

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Acute retinal necrosis (ARN) syndrome is a diffuse uveitis characterized by a peripheral necrotizing retinitis and retinal vasculitis. The authors document and discuss a case of ARN syndrome that initially presented with remarkable changes in the peripapillary retinal nerve fiber layer that they have termed arcuate neuroretinitis. These changes consisted of a well-defined arcuate band of retinitis paralleling the course of a parafoveal nerve fiber bundle. Evaluation of serial serum antibody titers suggests HSV-2 as a possible causative agent in this unique presentation of ARN syndrome.

Original languageEnglish
Pages (from-to)937-940
Number of pages4
Issue number7
StatePublished - Jan 1 1988


  • acute retinal necrosis
  • arcuate neuroretinitis
  • herpes simplex
  • retinitis


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