Acute Myocardial Infarction in Women: A Scientific Statement from the American Heart Association

Laxmi S. Mehta, Theresa M. Beckie, Holli A. DeVon, Cindy L. Grines, Harlan M. Krumholz, Michelle N. Johnson, Kathryn J. Lindley, Viola Vaccarino, Tracy Y. Wang, Karol E. Watson, Nanette K. Wenger

Research output: Contribution to journalReview articlepeer-review

930 Scopus citations

Abstract

Cardiovascular disease is the leading cause of mortality in American women. Since 1984, the annual cardiovascular disease mortality rate has remained greater for women than men; however, over the last decade, there have been marked reductions in cardiovascular disease mortality in women. The dramatic decline in mortality rates for women is attributed partly to an increase in awareness, a greater focus on women and cardiovascular disease risk, and the increased application of evidence-based treatments for established coronary heart disease. This is the first scientific statement from the American Heart Association on acute myocardial infarction in women. Sex-specific differences exist in the presentation, pathophysiological mechanisms, and outcomes in patients with acute myocardial infarction. This statement provides a comprehensive review of the current evidence of the clinical presentation, pathophysiology, treatment, and outcomes of women with acute myocardial infarction.

Original languageEnglish
Pages (from-to)916-947
Number of pages32
JournalCirculation
Volume133
Issue number9
DOIs
StatePublished - Mar 1 2016

Keywords

  • AHA Scientific Statements
  • cardiovascular diseases
  • coronary disease
  • myocardial infarction
  • women

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