Core Messages: Acute interstitial nephritis (AIN) is a term usually reserved for an allergic inflammation of the kidney, with characteristic eosinophilic infiltrates in the renal interstitium. AIN should be suspected in all cases of unexplained renal failure in the intensive care setting, where the incidence of this condition is much higher than in other settings. Common causes include drug-induced, certain infections or autoimmune processes. Withdrawal of the offending agent, if possible, and supportive therapy are the mainstays of management.
|Title of host publication||Pediatric Nephrology in the ICU|
|Publisher||Springer Berlin Heidelberg|
|Number of pages||8|
|State||Published - 2009|