Acute interstitial nephritis

V. R. Dharnidharka, C. E. Araya, D. D. Henry

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations


Core Messages: Acute interstitial nephritis (AIN) is a term usually reserved for an allergic inflammation of the kidney, with characteristic eosinophilic infiltrates in the renal interstitium. AIN should be suspected in all cases of unexplained renal failure in the intensive care setting, where the incidence of this condition is much higher than in other settings. Common causes include drug-induced, certain infections or autoimmune processes. Withdrawal of the offending agent, if possible, and supportive therapy are the mainstays of management.

Original languageEnglish
Title of host publicationPediatric Nephrology in the ICU
PublisherSpringer Berlin Heidelberg
Number of pages8
ISBN (Print)9783540744238
StatePublished - 2009


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