Acute Infective Endocarditis

Research output: Contribution to journalReview articlepeer-review

86 Scopus citations


Acute infective endocarditis is a complex disease with changing epidemiology and a rapidly evolving knowledge base. To consistently achieve optimal outcomes in the management of infective endocarditis, the clinical team must have an understanding of the epidemiology, microbiology, and natural history of infective endocarditis, as well as a grasp of guiding principles of diagnosis and medical and surgical management. The focus of this review is acute infective endocarditis, though many studies of diagnosis and treatment do not differentiate between acute and subacute disease, and indeed many principles of diagnosis and management of infective endocarditis for acute and subacute disease are identical.

Original languageEnglish
Pages (from-to)643-664
Number of pages22
JournalInfectious disease clinics of North America
Issue number3
StatePublished - Sep 2009


  • Antimicrobial agents
  • Critical care
  • Endocarditis
  • Heart valves
  • Thoracic surgery


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