TY - JOUR
T1 - Acute Disseminated Encephalomyelitis in Children
T2 - An Updated Review Based on Current Diagnostic Criteria
AU - Cole, Jordan
AU - Evans, Emily
AU - Mwangi, Martin
AU - Mar, Soe
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/11
Y1 - 2019/11
N2 - Acute disseminated encephalomyelitis is an inflammatory disorder of the central nervous system. Uniform diagnostic criteria for acute disseminated encephalomyelitis did not exist until publication of expert-defined consensus definitions by the International Pediatric Multiple Sclerosis Society Group in 2007, with updates in 2013. In the expanding field of pediatric neuroimmunology, consistent diagnostic criteria are essential to correctly categorize patients as increasing information regarding prognosis and management becomes available. Scientific literature is relatively lacking in review articles on International Pediatric Multiple Sclerosis Society Group-defined acute disseminated encephalomyelitis. This review focuses primarily on references applying the International Pediatric Multiple Sclerosis Society Group criteria for acute disseminated encephalomyelitis presenting specific, up-to-date, and translatable information regarding the epidemiology, pathophysiology, clinical features, diagnosis, management, and prognosis of acute disseminated encephalomyelitis in the pediatric population.
AB - Acute disseminated encephalomyelitis is an inflammatory disorder of the central nervous system. Uniform diagnostic criteria for acute disseminated encephalomyelitis did not exist until publication of expert-defined consensus definitions by the International Pediatric Multiple Sclerosis Society Group in 2007, with updates in 2013. In the expanding field of pediatric neuroimmunology, consistent diagnostic criteria are essential to correctly categorize patients as increasing information regarding prognosis and management becomes available. Scientific literature is relatively lacking in review articles on International Pediatric Multiple Sclerosis Society Group-defined acute disseminated encephalomyelitis. This review focuses primarily on references applying the International Pediatric Multiple Sclerosis Society Group criteria for acute disseminated encephalomyelitis presenting specific, up-to-date, and translatable information regarding the epidemiology, pathophysiology, clinical features, diagnosis, management, and prognosis of acute disseminated encephalomyelitis in the pediatric population.
KW - Acute disseminated encephalomyelitis
KW - International Pediatric Multiple Sclerosis Society Group diagnostic criteria
KW - Pediatric demyelinating disease
KW - Topical review
UR - http://www.scopus.com/inward/record.url?scp=85069819631&partnerID=8YFLogxK
U2 - 10.1016/j.pediatrneurol.2019.06.017
DO - 10.1016/j.pediatrneurol.2019.06.017
M3 - Review article
C2 - 31371120
AN - SCOPUS:85069819631
SN - 0887-8994
VL - 100
SP - 26
EP - 34
JO - Pediatric Neurology
JF - Pediatric Neurology
ER -