TY - JOUR
T1 - Active reward processing during human sleep
T2 - Insights from sleep-related eating disorder
AU - Perogamvros, Lampros
AU - Baud, Patrick
AU - Hasler, Roland
AU - Cloninger, Claude Robert
AU - Schwartz, Sophie
AU - Perrig, Stephen
PY - 2012
Y1 - 2012
N2 - In this paper, we present two carefully documented cases of patients with sleep-related eating disorder (SRED), a parasomnia which is characterized by involuntary compulsive eating during the night and whose pathophysiology is not known. Using videopolysomnography, a dream diary and psychometric examination, we found that both patients present elevated novelty seeking and increased reward sensitivity. In light of new evidence on the mesolimbic dopaminergic implication in compulsive eating disorders, our findings suggest a role of an active reward system during sleep in the manifestation of SRED.
AB - In this paper, we present two carefully documented cases of patients with sleep-related eating disorder (SRED), a parasomnia which is characterized by involuntary compulsive eating during the night and whose pathophysiology is not known. Using videopolysomnography, a dream diary and psychometric examination, we found that both patients present elevated novelty seeking and increased reward sensitivity. In light of new evidence on the mesolimbic dopaminergic implication in compulsive eating disorders, our findings suggest a role of an active reward system during sleep in the manifestation of SRED.
KW - Dreaming
KW - Mesolimbic dopaminergic system
KW - Parasomnias
KW - Reward processing
KW - Sleep
KW - Sleep-related eating disorder
UR - http://www.scopus.com/inward/record.url?scp=84870876723&partnerID=8YFLogxK
U2 - 10.3389/fneur.2012.00168
DO - 10.3389/fneur.2012.00168
M3 - Article
C2 - 23205019
AN - SCOPUS:84870876723
SN - 1664-2295
VL - NOV
JO - Frontiers in Neurology
JF - Frontiers in Neurology
M1 - Article 168
ER -