Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: Role of Ack1 in polyubiquitination of tumor suppressor Wwox

Keyphrases

• ACK1 100%
• Activated Cdc42-associated Kinase 6%
• Anchorage-independent Growth 6%
• Androgen-independent 6%
• Apoptotic Activity 6%
• Benign Prostate Disease 6%
• Dissociation 6%
• Geldanamycin 6%
• Growth in Vitro 6%
• Heat Shock Protein 90 (Hsp90) 6%
• Heat Shock Protein 90 Inhibitor 6%
• Human Cancer 6%
• Interacting Proteins 6%
• Kinase Activity 6%
• LNCaP Cells 6%
• Molecular Chaperone 6%
• Novel Therapeutic Targets 6%
• Nude Mice 6%
• Pathologic Conditions 6%
• Phosphorylation 13%
• Polyubiquitination 100%
• Pro-apoptotic 6%
• Prostate Cancer 6%
• Prostate Tumor 6%
• Prostate Tumorigenesis 100%
• Signal Properties 6%
• Site-directed mutagenesis 6%
• Splice Variant 6%
• Tumor Suppressor 100%
• Tumorigenesis 13%
• Tyrosine 20%
• Tyrosine Kinase 100%
• Tyrosine Phosphorylation 6%
• Tyrosine Residue 6%
• WW Domain-containing Oxidoreductase 6%
• Wwox 100%

Biochemistry, Genetics and Molecular Biology

• Anchorage Independent Growth 20%
• Carcinogenesis 100%
• Chaperone Protein 20%
• Geldanamycin 20%
• Heat Shock Protein 20%
• Heat Shock Protein 90 Inhibitor 20%
• Kinase 40%
• LNCaP 20%
• Nude Mouse 20%
• Oxidoreductase 20%
• Phosphotransferase 40%
• Receptor Tyrosine Kinase 100%
• Site-Directed Mutagenesis 20%
• Tumor Suppressor Protein 100%
• Tyrosine 100%
• Tyrosine Kinase 100%
• Tyrosine Phosphorylation 20%
• WW Domain 20%