Acoustic tumor growth: Implications for treatment choices

Michael J. Fucci, Craig A. Buchman, Derald E. Brackmann, Karen I. Berliner

Research output: Contribution to journalArticlepeer-review

115 Scopus citations

Abstract

Background: Knowledge of acoustic neuroma (AN) growth is essential for treatment planning. Methods: A retrospective analysis of 119 patients with AN (mean age, 65 years; range, 37-84 years) followed with interval magnetic resonance imagings (MRIs) was performed. Change in maximum tumor dimension as a function of follow-up period was analyzed. Results: Overall, maximum tumor dimension increased >2 mm in only 30% of patients. Of those that grew, the mean growth rate was 3.8 mm/year (maximum, 25 mm/year). Age, gender, and laterality did not predict growth. Most tumors that grew (86.1%) were <20 mm at presentation. However, tumors >20 mm were statistically more likely to grow (71%, p = 0.028). Conclusions: Most ANs followed with periodic MRIs do not grow. Available clinical information usually cannot predict growth. Serial MR is are advocated for all patients treated with observation.

Original languageEnglish
Pages (from-to)495-499
Number of pages5
JournalAmerican Journal of Otology
Volume20
Issue number4
StatePublished - Jul 1 1999

Keywords

  • Acoustic neuroma
  • Microsurgery
  • Stereotactic radiation
  • Tumor growth

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