Accuracy of transrectal ultrasound in predicting pathologic stage of rectal cancer before and after preoperative radiation therapy

James W. Fleshman, Robert J. Myerson, Robert D. Fry, Ira J. Kodner

    Research output: Contribution to journalArticlepeer-review

    81 Scopus citations

    Abstract

    Transrectal ultrasound (TRUS) and CT scan staging of rectal cancers before, and TRUS staging after, 45 Gy of irradiation were compared with the pathologic stage of the resected specimen in 19 patients. Accuracy of TRUS before and after irradiation, and of CT scan before irradiation, was 32 percent, 63 percent, and 53 percent, respectively. CT scan before and TRUS after irradiation predicted lymph node involvement in 79 percent and 68 percent of cases, respectively. Positive predictive value for lymph node involvement before irradiation was 60 percent for CT scan and 37.5 percent for TRUS; after irradiation, it was 50 percent for TRUS. Negative predictive value was 100 percent for CT scan and TRUS before radiation and 88 percent for TRUS after irradiation. Preoperative radiation therapy makes TRUS and CT scan less effective as staging techniques. The absence of lymph nodes on TRUS and CT scan before and after irradiation is reliable.

    Original languageEnglish
    Pages (from-to)823-829
    Number of pages7
    JournalDiseases of the Colon & Rectum
    Volume35
    Issue number9
    DOIs
    StatePublished - Sep 1 1992

    Keywords

    • External beam radiation
    • Lymph node detection
    • Rectal cancer
    • Transrectal ultrasound staging

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