TY - JOUR
T1 - Accuracy of transrectal ultrasound in predicting pathologic stage of rectal cancer before and after preoperative radiation therapy
AU - Fleshman, James W.
AU - Myerson, Robert J.
AU - Fry, Robert D.
AU - Kodner, Ira J.
PY - 1992/9/1
Y1 - 1992/9/1
N2 - Transrectal ultrasound (TRUS) and CT scan staging of rectal cancers before, and TRUS staging after, 45 Gy of irradiation were compared with the pathologic stage of the resected specimen in 19 patients. Accuracy of TRUS before and after irradiation, and of CT scan before irradiation, was 32 percent, 63 percent, and 53 percent, respectively. CT scan before and TRUS after irradiation predicted lymph node involvement in 79 percent and 68 percent of cases, respectively. Positive predictive value for lymph node involvement before irradiation was 60 percent for CT scan and 37.5 percent for TRUS; after irradiation, it was 50 percent for TRUS. Negative predictive value was 100 percent for CT scan and TRUS before radiation and 88 percent for TRUS after irradiation. Preoperative radiation therapy makes TRUS and CT scan less effective as staging techniques. The absence of lymph nodes on TRUS and CT scan before and after irradiation is reliable.
AB - Transrectal ultrasound (TRUS) and CT scan staging of rectal cancers before, and TRUS staging after, 45 Gy of irradiation were compared with the pathologic stage of the resected specimen in 19 patients. Accuracy of TRUS before and after irradiation, and of CT scan before irradiation, was 32 percent, 63 percent, and 53 percent, respectively. CT scan before and TRUS after irradiation predicted lymph node involvement in 79 percent and 68 percent of cases, respectively. Positive predictive value for lymph node involvement before irradiation was 60 percent for CT scan and 37.5 percent for TRUS; after irradiation, it was 50 percent for TRUS. Negative predictive value was 100 percent for CT scan and TRUS before radiation and 88 percent for TRUS after irradiation. Preoperative radiation therapy makes TRUS and CT scan less effective as staging techniques. The absence of lymph nodes on TRUS and CT scan before and after irradiation is reliable.
KW - External beam radiation
KW - Lymph node detection
KW - Rectal cancer
KW - Transrectal ultrasound staging
UR - http://www.scopus.com/inward/record.url?scp=0026806407&partnerID=8YFLogxK
U2 - 10.1007/BF02047866
DO - 10.1007/BF02047866
M3 - Article
C2 - 1511639
AN - SCOPUS:0026806407
SN - 0012-3706
VL - 35
SP - 823
EP - 829
JO - Diseases of the Colon & Rectum
JF - Diseases of the Colon & Rectum
IS - 9
ER -