Accumulation of odd chain length acyl moieties in 3T3-L1 cells during insulin-induced differentiation to fat cells: Identification of α-oxidation in mammalian cells

Xiong Su, Xianlin Man, Richard W. Gross

Research output: Contribution to conferencePaperpeer-review

Abstract

The accumulation of odd chain length acyl moieties in 3T3-L1 cells during insulin-induced differentiation to the fat cells was investigated. The fatty acyl moieties are accumulated in multiple phospholipid classes during alterations in lipid metabolism in adipocyte differentiation. The electrospray ionization mass spectrometry (ESI MS) was used to study the lipid metabolism during cell differentiation. The GC/EI/MS analysis were performed to study the accumulation of acyl moieties. The results show the accumulation of acyl moieties with molecular weights corresponding to odd chain length fatty acids of C15:0 and C17:).

Original languageEnglish
Pages601-602
Number of pages2
StatePublished - 2002
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002Jun 6 2002

Conference

ConferenceProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Country/TerritoryUnited States
CityOrlando, FL
Period06/2/0206/6/02

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