Abnormal Glucose Counterregulation in Insulin-Dependent Diabetes Mellitus

To the Editor: I wish to raise two points concerning the article in which Bolli and associates discuss the abnormal glucose counterregulation in patients with Type I diabetes (June 28 issue).¹ First, the clinical and more important one: I would hope that Journal readers would not abandon their attempts to achieve tight diabetic control but would simply approach it more cautiously in most patients with Type I disease. The evidence is substantial that if only strict control could be achieved, diabetic retinopathy, nephropathy, and neuropathy would be delayed and perhaps lessened.² In recent years there have been concerted efforts by.