Ablation of soft tissue at 6.45 μm using a strontium vapor laser

Mark A. Mackanos, Borislav Ivanov, A. N. Soldatov, I. Kostadinov, Marcus H. Mendenhall, David W. Piston, Richard F. Haglund, E. Duco Jansen

Research output: Contribution to journalConference articlepeer-review

13 Scopus citations

Abstract

A gas discharge strontium vapor laser has been shown to operate with up to 90% of its light emitted at 6.45 μm. We have investigated the use of this laser as a potential stand-alone, tabletop alternative to the FEL for ablation of soft tissue. This custom-made laser currently delivers up to 2.4 watts of average power at 13 kHz pulse repetition rate (range 5-20 kHz). Despite a poor spatial beam profile the laser has been shown to ablate both water and soft tissue. However, current pulse energies (< 185 μJ) are insufficient for single pulse ablation even when focused to the smallest possible spot size (130 μm). Instead, the high pulse repetition rate causes the ablation to occur in a quasi CW manner. The dynamics of ablation studied by pump-probe (Schlieren) imaging and macroscopic white light imaging showed micro-explosions but at a rate well below the pulse repetition frequency. Histological analysis of ablation craters in bovine muscle exhibited significant collateral thermal damage, consistent with the high pulse frequency, thermal superposition and heat diffusion. Efforts to increase the pulse energy in order to achieve the threshold for pulse-to-pulse ablation are ongoing and will be discussed.

Original languageEnglish
Pages (from-to)201-208
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5319
DOIs
StatePublished - Oct 27 2004
Externally publishedYes
EventProgress in Biomedical Optics and Imaging - Laser Interaction with Tissue and Cells XV - San Jose, CA, United States
Duration: Jan 26 2004Jan 28 2004

Keywords

  • 6.45 μm
  • Ablation
  • Soft tissue
  • Strontium vapor, laser

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