Aberrant properties of alkaline phosphatase in patient fibroblasts correlate with clinical expressivity in severe forms of hypophosphatasia

Keyphrases

• Alkaline Phosphatase Activity 100%
• Hypophosphatasia 100%
• Alkaline Phosphatase 100%
• Severe Disease 100%
• Patient Fibroblasts 100%
• TNSALP 60%
• Fibroblasts 40%
• Biochemical Properties 40%
• Bone Alkaline Phosphatase 40%
• Cross-reacting Material 197 40%
• Liver 20%
• Disease Severity 20%
• Autosomal Recessive 20%
• Kidney 20%
• Gene mutation 20%
• Isoenzymes 20%
• Strong Correlation 20%
• In(III) 20%
• Gel Filtration 20%
• Control Cell 20%
• Clinical Severity 20%
• Missense mutation 20%
• Metabolic Bone Disease 20%
• Means of Control 20%
• Aberrancy 20%
• Subject Group 20%
• Electrodialysis 20%
• Material Level 20%
• Enzyme Properties 20%

Biochemistry, Genetics and Molecular Biology

• Alkaline Phosphatase 100%
• Fibroblast 100%
• Enzyme 8%
• Gene Mutation 8%
• Isoenzyme 8%
• Gel Filtration 8%
• Autosomal Recessive Inheritance 8%
• Missense Mutation 8%
• Enzyme Property 8%
• Electrodialysis 8%