A whole-genome simulator capable of modeling high-order epistasis for complex disease

Keyphrases

• Genome-wide Association Study 100%
• Complex Disease 100%
• Whole Genome 100%
• High-order Epistasis 100%
• Disease Model 40%
• Linkage Disequilibrium 40%
• Penetrance 40%
• Joint Effect 40%
• Marginal Effects 40%
• Single nucleotide Polymorphism 20%
• Multilocus Approach 20%
• Logistic Regression Model 20%
• Sampling numbers 20%
• Risk Variant 20%
• Complex Interactions 20%
• Biological Interactions 20%
• Interaction Model 20%
• Epistasis 20%
• New Risks 20%
• Product Terms 20%
• Multiple Loci 20%
• Accurate Modeling 20%
• Lower Order 20%
• Single Marker 20%
• Genetic Simulation 20%
• Pairwise Interaction 20%
• Model Specification 20%
• Higher-order Interactions 20%
• Single nucleotide Polymorphism Effect 20%
• Interaction Products 20%
• Data Simulator 20%

Biochemistry, Genetics and Molecular Biology

• Genome-Wide Association Study 100%
• Single-Nucleotide Polymorphism 40%
• Gene Linkage Disequilibrium 40%
• Penetrance 40%
• DNA Template 20%