TY - JOUR
T1 - A twin study of inattentive, aggressive, and anxious/depressed behaviors
AU - Hudziak, James J.
AU - Rudiger, Lawrence P.
AU - Neale, Michael C.
AU - Heath, Andrew C.
AU - Todd, Richard D.
N1 - Funding Information:
This work was supported by NIMH grant MH52813 .
PY - 2000
Y1 - 2000
N2 - Objective: To estimate genetic, environmental, and rater contrast influences on parental report of Attention Problems (AP), Aggressive (Agg), and Anxious/Depressed (AxD) behaviors of 492 twin pairs assessed with the Child Behavior Checklist. Method: A parent (92% mothers) of twins aged 8 to 12 years Completed the Child Behavior Checklist. Genetic, shared and unique environmental, and rater bias effects were estimated for the AP, Agg, and AxD syndromes. Data on boys and girls were analyzed separately. Results were compared to prior research on related DSM disorders. Results: Estimates of genetic influences on AP (60%-68%), Agg (70%-77%), and AxD (61%-65%) were high for both sexes, but lower for AP than prior findings using DSM attention-deficit hyperactivity disorder (ADHD). However, unlike equivalent analyses of DSM ADHD based on parental report, there was no evidence of rater bias. Conclusions: Estimates of genetic influence on these common child psychopathological domains were high. There was no evidence of rater contrast effects. These findings have implications for diagnosis, particularly when assessing families with multiple children.
AB - Objective: To estimate genetic, environmental, and rater contrast influences on parental report of Attention Problems (AP), Aggressive (Agg), and Anxious/Depressed (AxD) behaviors of 492 twin pairs assessed with the Child Behavior Checklist. Method: A parent (92% mothers) of twins aged 8 to 12 years Completed the Child Behavior Checklist. Genetic, shared and unique environmental, and rater bias effects were estimated for the AP, Agg, and AxD syndromes. Data on boys and girls were analyzed separately. Results were compared to prior research on related DSM disorders. Results: Estimates of genetic influences on AP (60%-68%), Agg (70%-77%), and AxD (61%-65%) were high for both sexes, but lower for AP than prior findings using DSM attention-deficit hyperactivity disorder (ADHD). However, unlike equivalent analyses of DSM ADHD based on parental report, there was no evidence of rater bias. Conclusions: Estimates of genetic influence on these common child psychopathological domains were high. There was no evidence of rater contrast effects. These findings have implications for diagnosis, particularly when assessing families with multiple children.
KW - Aggression
KW - Anxious/depressed behavior
KW - Attention
KW - Attention-deficit hyperactivity disorder
KW - Informant effects
KW - Twins
UR - http://www.scopus.com/inward/record.url?scp=0034126980&partnerID=8YFLogxK
U2 - 10.1097/00004583-200004000-00016
DO - 10.1097/00004583-200004000-00016
M3 - Article
C2 - 10761349
AN - SCOPUS:0034126980
SN - 0890-8567
VL - 39
SP - 469
EP - 476
JO - Journal of the American Academy of Child and Adolescent Psychiatry
JF - Journal of the American Academy of Child and Adolescent Psychiatry
IS - 4
ER -