A time-embedding network models the ontogeny of 23 hepatic drug metabolizing enzymes

Keyphrases

• Drug-metabolizing Enzymes 100%
• Network Model 100%
• Time Embedding 100%
• Embedded Networks 100%
• Age-related Changes 50%
• Drug Toxicity 33%
• Drug Metabolism Enzyme 33%
• Pediatric Patients 16%
• Clinical Data 16%
• Adulthood 16%
• Neural Network 16%
• Metabolism 16%
• Age-dependent 16%
• Enzyme Expression 16%
• Pediatric Population 16%
• Demographic Factors 16%
• Risk Assessment 16%
• Adverse Drug Reaction 16%
• Absorption Distribution 16%
• Metabolic Enzymes 16%
• Drug Safety 16%
• Nonlinear Dynamics 16%
• Reactive Metabolites 16%
• Toxicity Risk 16%
• Valproic Acid 16%
• Lack of Information 16%
• Fetal Period 16%
• Standard Neural Network 16%
• Population-level Variation 16%
• Valproic Acid Toxicity 16%
• Dextromethorphan 16%
• Embedding Model 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Drug Metabolizing Enzyme 100%
• Drug Metabolism 100%
• Sodium Valproate 100%
• Drug Toxicity 100%
• Elimination 50%
• Adverse Drug Reaction 50%
• Drug Safety 50%
• Dextromethorphan 50%