A technique for placing ventriculoperitoneal shunts in a neonatal model of hydrocephalus

Thomas J. Lovely; David W. Miller; James P. McAllister

doi:10.1016/0165-0270(89)90144-1

A technique for placing ventriculoperitoneal shunts in a neonatal model of hydrocephalus

Thomas J. Lovely, David W. Miller, James P. McAllister

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Induction of hydrocephalus in a neonatal animal with subsequent surgical decompression is the most analogous situation to the clinical state of infantile hydrocephalus. Described in detail is a reliable method for the placement of pressure-dependent ventriculoperitoneal shunts in neonatal kittens with hydrocephalus. Successful decompression can be quantified using ultrasound. This model allows for observation of hydrocephalic changes that may persist or be corrected after shunting, be they morphological, behavioral or biochemical. In addition, potential pitfalls in performing the procedure and in postoperative care of the kittens are addressed.

Original language	English
Pages (from-to)	201-206
Number of pages	6
Journal	Journal of Neuroscience Methods
Volume	29
Issue number	3
DOIs	https://doi.org/10.1016/0165-0270(89)90144-1
State	Published - Sep 1989

Keywords

Hydrocephalus
Neonatal cat
Surgical technique
Ventriculoperitoneal shunt

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10.1016/0165-0270(89)90144-1

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title = "A technique for placing ventriculoperitoneal shunts in a neonatal model of hydrocephalus",

abstract = "Induction of hydrocephalus in a neonatal animal with subsequent surgical decompression is the most analogous situation to the clinical state of infantile hydrocephalus. Described in detail is a reliable method for the placement of pressure-dependent ventriculoperitoneal shunts in neonatal kittens with hydrocephalus. Successful decompression can be quantified using ultrasound. This model allows for observation of hydrocephalic changes that may persist or be corrected after shunting, be they morphological, behavioral or biochemical. In addition, potential pitfalls in performing the procedure and in postoperative care of the kittens are addressed.",

keywords = "Hydrocephalus, Neonatal cat, Surgical technique, Ventriculoperitoneal shunt",

author = "Lovely, {Thomas J.} and Miller, {David W.} and McAllister, {James P.}",

note = "Funding Information: The authors wish to thank William A. Buch-heit, M.D. Chairman of the Department of Neurosurgery. Temple University Hospital for his continued encouragement and support. We are also grateful to Barbara Wolfson, M.D., Raymond C. Truex Jr, M.D. and Arnold G. Salotto, M.D. for their technical contributions, and Cherie Glanz-man and Diane Davis for secretarial assistance. This work was supported in part by Biomedical Research Support Grant SO RR05417 from the Division of Research Resources, National Institute of Health awarded to J.P.M.",

year = "1989",

month = sep,

doi = "10.1016/0165-0270(89)90144-1",

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pages = "201--206",

journal = "Journal of Neuroscience Methods",

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T1 - A technique for placing ventriculoperitoneal shunts in a neonatal model of hydrocephalus

AU - Lovely, Thomas J.

AU - Miller, David W.

AU - McAllister, James P.

N1 - Funding Information: The authors wish to thank William A. Buch-heit, M.D. Chairman of the Department of Neurosurgery. Temple University Hospital for his continued encouragement and support. We are also grateful to Barbara Wolfson, M.D., Raymond C. Truex Jr, M.D. and Arnold G. Salotto, M.D. for their technical contributions, and Cherie Glanz-man and Diane Davis for secretarial assistance. This work was supported in part by Biomedical Research Support Grant SO RR05417 from the Division of Research Resources, National Institute of Health awarded to J.P.M.

PY - 1989/9

Y1 - 1989/9

N2 - Induction of hydrocephalus in a neonatal animal with subsequent surgical decompression is the most analogous situation to the clinical state of infantile hydrocephalus. Described in detail is a reliable method for the placement of pressure-dependent ventriculoperitoneal shunts in neonatal kittens with hydrocephalus. Successful decompression can be quantified using ultrasound. This model allows for observation of hydrocephalic changes that may persist or be corrected after shunting, be they morphological, behavioral or biochemical. In addition, potential pitfalls in performing the procedure and in postoperative care of the kittens are addressed.

AB - Induction of hydrocephalus in a neonatal animal with subsequent surgical decompression is the most analogous situation to the clinical state of infantile hydrocephalus. Described in detail is a reliable method for the placement of pressure-dependent ventriculoperitoneal shunts in neonatal kittens with hydrocephalus. Successful decompression can be quantified using ultrasound. This model allows for observation of hydrocephalic changes that may persist or be corrected after shunting, be they morphological, behavioral or biochemical. In addition, potential pitfalls in performing the procedure and in postoperative care of the kittens are addressed.

KW - Hydrocephalus

KW - Neonatal cat

KW - Surgical technique

KW - Ventriculoperitoneal shunt

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U2 - 10.1016/0165-0270(89)90144-1

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JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

SN - 0165-0270

IS - 3

ER -

A technique for placing ventriculoperitoneal shunts in a neonatal model of hydrocephalus

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Keywords

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