Abstract
Induction of hydrocephalus in a neonatal animal with subsequent surgical decompression is the most analogous situation to the clinical state of infantile hydrocephalus. Described in detail is a reliable method for the placement of pressure-dependent ventriculoperitoneal shunts in neonatal kittens with hydrocephalus. Successful decompression can be quantified using ultrasound. This model allows for observation of hydrocephalic changes that may persist or be corrected after shunting, be they morphological, behavioral or biochemical. In addition, potential pitfalls in performing the procedure and in postoperative care of the kittens are addressed.
| Original language | English |
|---|---|
| Pages (from-to) | 201-206 |
| Number of pages | 6 |
| Journal | Journal of Neuroscience Methods |
| Volume | 29 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 1989 |
| Externally published | Yes |
Keywords
- Hydrocephalus
- Neonatal cat
- Surgical technique
- Ventriculoperitoneal shunt
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Lovely, T. J., Miller, D. W., & McAllister, J. P. (1989). A technique for placing ventriculoperitoneal shunts in a neonatal model of hydrocephalus. Journal of Neuroscience Methods, 29(3), 201-206. https://doi.org/10.1016/0165-0270(89)90144-1