A technique for placing ventriculoperitoneal shunts in a neonatal model of hydrocephalus

Thomas J. Lovely, David W. Miller, James P. McAllister

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Induction of hydrocephalus in a neonatal animal with subsequent surgical decompression is the most analogous situation to the clinical state of infantile hydrocephalus. Described in detail is a reliable method for the placement of pressure-dependent ventriculoperitoneal shunts in neonatal kittens with hydrocephalus. Successful decompression can be quantified using ultrasound. This model allows for observation of hydrocephalic changes that may persist or be corrected after shunting, be they morphological, behavioral or biochemical. In addition, potential pitfalls in performing the procedure and in postoperative care of the kittens are addressed.

Original languageEnglish
Pages (from-to)201-206
Number of pages6
JournalJournal of Neuroscience Methods
Volume29
Issue number3
DOIs
StatePublished - Sep 1989
Externally publishedYes

Keywords

  • Hydrocephalus
  • Neonatal cat
  • Surgical technique
  • Ventriculoperitoneal shunt

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