Abstract
The sulfate donor 3′-phosphoadenosine-5′-phosphosulfate (PAPS) is a near-universal component of sulfur metabolism. In a report by Zhang et al. in this issue of Structure, X-ray crystal structures of the APS kinase domains from human PAPS synthase reveal dynamic substrate recognition and a regulatory “redox switch” analogous to that previously described only in plant APS kinases.
Original language | English |
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Pages (from-to) | 757-759 |
Number of pages | 3 |
Journal | Structure |
Volume | 31 |
Issue number | 7 |
DOIs |
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State | Published - Jul 6 2023 |