TY - JOUR
T1 - A single-question screen for rapid eye movement sleep behavior disorder
T2 - A multicenter validation study
AU - Postuma, Ronald B.
AU - Arnulf, Isabelle
AU - Hogl, Birgit
AU - Iranzo, Alex
AU - Miyamoto, Tomoyuki
AU - Dauvilliers, Yves
AU - Oertel, Wolfgang
AU - Ju, Yo El
AU - Puligheddu, Monica
AU - Jennum, Poul
AU - Pelletier, Amelie
AU - Wolfson, Christina
AU - Leu-Semenescu, Smaranda
AU - Frauscher, Birgit
AU - Miyamoto, Masayuki
AU - Cochen De Cock, Valerie
AU - Unger, Marcus M.
AU - Stiasny-Kolster, Karin
AU - Livia Fantini, Maria
AU - Montplaisir, Jacques Y.
PY - 2012/6
Y1 - 2012/6
N2 - Background: Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia that is an important risk factor for Parkinson's disease (PD) and Lewy body dementia. Its prevalence is unknown. One barrier to determining prevalence is that current screening tools are too long for large-scale epidemiologic surveys. Therefore, we designed the REM Sleep Behavior Disorder Single-Question Screen (RBD1Q), a screening question for dream enactment with a simple yes/no response. Methods:: Four hundred and eighty-four sleep-clinic-based participants (242 idiopathic RBD patients and 242 controls) completed the screen during a multicenter case-control study. All participants underwent a polysomnogram to define gold-standard diagnosis according to standard criteria. Results:: We found a sensitivity of 93.8% and a specificity of 87.2%. Sensitivity and specificity were similar in healthy volunteers, compared to controls or patients with other sleep diagnoses. Conclusions:: A single-question screen for RBD may reliably detect disease, with psychometric properties favorably comparable to those reported for longer questionnaires.
AB - Background: Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia that is an important risk factor for Parkinson's disease (PD) and Lewy body dementia. Its prevalence is unknown. One barrier to determining prevalence is that current screening tools are too long for large-scale epidemiologic surveys. Therefore, we designed the REM Sleep Behavior Disorder Single-Question Screen (RBD1Q), a screening question for dream enactment with a simple yes/no response. Methods:: Four hundred and eighty-four sleep-clinic-based participants (242 idiopathic RBD patients and 242 controls) completed the screen during a multicenter case-control study. All participants underwent a polysomnogram to define gold-standard diagnosis according to standard criteria. Results:: We found a sensitivity of 93.8% and a specificity of 87.2%. Sensitivity and specificity were similar in healthy volunteers, compared to controls or patients with other sleep diagnoses. Conclusions:: A single-question screen for RBD may reliably detect disease, with psychometric properties favorably comparable to those reported for longer questionnaires.
KW - Diagnosis
KW - REM sleep behavior disorder
KW - Screening
UR - http://www.scopus.com/inward/record.url?scp=84862667387&partnerID=8YFLogxK
U2 - 10.1002/mds.25037
DO - 10.1002/mds.25037
M3 - Article
C2 - 22729987
AN - SCOPUS:84862667387
SN - 0885-3185
VL - 27
SP - 913
EP - 916
JO - Movement Disorders
JF - Movement Disorders
IS - 7
ER -