A single-cell window into pancreas cancer fibroblast heterogeneity

Jad I. Belle, David G. Denardo

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Cancer-associated fibroblasts (CAF) have been implicated in diverse and sometimes divergent tumor modulatory processes that can be explained only by the existence of heterogeneous CAF subsets. In this issue of Cancer Discovery, Elyada and colleagues utilize single-cell transcriptomics to resolve CAF heterogeneity in pancreatic ductal adenocarcinoma and identify a novel antigen-presenting CAF population.

Original languageEnglish
Pages (from-to)1001-1002
Number of pages2
JournalCancer discovery
Volume9
Issue number8
DOIs
StatePublished - Aug 2019

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