A Simplified Test of Epinephrine Responsiveness

Michael A. Kass, Bernard Becker

Research output: Contribution to journalArticlepeer-review


Forty-three ocular hypertensive and 33 ocular normotensive subjects received two doses of topical 1% epinephrine hydrochloride in one eye. The epinephrine was administered twice, ie, at time “zero” (8 am) and 12 hours later (at 8 pm). The mean intraocular pressure responses at four hours and at 24 hours (12 hours after the last dose of epinephrine) were significantly correlated, r = 0.59 (P <.001). This suggested that the simpler four-hour test was an equally accurate measure of the ocular responsiveness to topical epinephrine.

Original languageEnglish
Pages (from-to)999-1000
Number of pages2
JournalArchives of Ophthalmology
Issue number6
StatePublished - Jun 1978


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