A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning

Jana K. Shirey, Ashley E. Brady, Paulianda J. Jones, Albert A. Davis, Thomas M. Bridges, J. Phillip Kennedy, Satyawan B. Jadhav, Usha N. Menon, Zixiu Xiang, Mona L. Watson, Edward P. Christian, James J. Doherty, Michael C. Quirk, Dean H. Snyder, James J. Lah, Allan I. Levey, Michelle M. Nicolle, Craig W. Lindsley, P. Jeffrey Conn

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Biochemistry, Genetics and Molecular Biology

Neuroscience

Pharmacology, Toxicology and Pharmaceutical Science