A revised nomenclature for the human and rodent α-tubulin gene family

Varsha K. Khodiyar; Lois J. Maltais; Katherine M.B. Sneddon; Jennifer R. Smith; Mary Shimoyama; Fernando Cabral; Charles Dumontet; Susan K. Dutcher; Robert J. Harvey; Laurence Lafanechère; John M. Murray; Eva Nogales; David Piquemal; Fabio Stanchi; Sue Povey; Ruth C. Lovering

doi:10.1016/j.ygeno.2007.04.008

A revised nomenclature for the human and rodent α-tubulin gene family

Varsha K. Khodiyar, Lois J. Maltais, Katherine M.B. Sneddon, Jennifer R. Smith, Mary Shimoyama, Fernando Cabral, Charles Dumontet, Susan K. Dutcher, Robert J. Harvey, Laurence Lafanechère, John M. Murray, Eva Nogales, David Piquemal, Fabio Stanchi, Sue Povey, Ruth C. Lovering

Research output: Contribution to journal › Article › peer-review

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Abstract

An essential component of microtubules, α-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat α-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field.

Original language	English
Pages (from-to)	285-289
Number of pages	5
Journal	Genomics
Volume	90
Issue number	2
DOIs	https://doi.org/10.1016/j.ygeno.2007.04.008
State	Published - Aug 2007

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Khodiyar, V. K., Maltais, L. J., Sneddon, K. M. B., Smith, J. R., Shimoyama, M., Cabral, F., Dumontet, C., Dutcher, S. K., Harvey, R. J., Lafanechère, L., Murray, J. M., Nogales, E., Piquemal, D., Stanchi, F., Povey, S., & Lovering, R. C. (2007). A revised nomenclature for the human and rodent α-tubulin gene family. Genomics, 90(2), 285-289. https://doi.org/10.1016/j.ygeno.2007.04.008

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abstract = "An essential component of microtubules, α-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat α-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field.",

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AU - Smith, Jennifer R.

AU - Shimoyama, Mary

AU - Cabral, Fernando

AU - Dumontet, Charles

AU - Dutcher, Susan K.

AU - Harvey, Robert J.

AU - Lafanechère, Laurence

AU - Murray, John M.

AU - Nogales, Eva

AU - Piquemal, David

AU - Stanchi, Fabio

AU - Povey, Sue

AU - Lovering, Ruth C.

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A revised nomenclature for the human and rodent α-tubulin gene family

Abstract

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