TY - JOUR
T1 - A randomized clinical trial to reduce asthma morbidity among inner-city children
T2 - Results of the national cooperative inner-city asthma study
AU - Evans, Richard
AU - Gergen, Peter J.
AU - Mitchell, Herman
AU - Kattan, Meyer
AU - Kercsmar, Carolyn
AU - Crain, Ellen
AU - Anderson, John
AU - Eggleston, Peyton
AU - Malveaux, Floyd J.
AU - Wedner, H. James
N1 - Funding Information:
Supported by grants UO1 A1-30751, A1-30752, A1-30756, A1-30772, A1-30773-01, A1-30777, A1-30779, A1-30780, and N01 A1-15105 from the National Institute of Allergy and Infectious Disease (National Institutes of Health, Bethesda, Maryland).
PY - 1999
Y1 - 1999
N2 - Objective: To evaluate a family-focused asthma intervention designed for inner-city children 5 to 11 years old with moderate to severe asthma. Study design: Randomized, multisite, controlled trial to minimize symptom days (wheeze, loss of sleep, reduction in play activity) measured by a 2-week recall assessed at 2-month intervals over a 2-year follow-up period. The intervention was tailored to each family's individual asthma risk profile assessed at baseline. Results: Averaged over the first 12 months, participants in the intervention group (n = 515) reported 3.51 symptom days in the 2 weeks before each follow-up interview compared with 4.06 symptom days for the control group (n = 518), a difference of 0.55 (95% CI, 0.18 to 0.92, P = .004). The reduction among children with severe asthma was approximately 3 times greater (1.54 d/2 wk). More children in the control group (18.9%) were hospitalized during the intervention compared with children in the intervention group (14.8%), a decrease of 4.19% (CI, -8.75 to 0.36, P = .071). These improvements were maintained in the intervention group during the second year of follow-up, during which they did not have access to the asthma counselor. Conclusions: We demonstrated that an individually tailored, multifaceted intervention carried out by Masters-level social workers trained in asthma management can reduce asthma symptoms among children in the inner city.
AB - Objective: To evaluate a family-focused asthma intervention designed for inner-city children 5 to 11 years old with moderate to severe asthma. Study design: Randomized, multisite, controlled trial to minimize symptom days (wheeze, loss of sleep, reduction in play activity) measured by a 2-week recall assessed at 2-month intervals over a 2-year follow-up period. The intervention was tailored to each family's individual asthma risk profile assessed at baseline. Results: Averaged over the first 12 months, participants in the intervention group (n = 515) reported 3.51 symptom days in the 2 weeks before each follow-up interview compared with 4.06 symptom days for the control group (n = 518), a difference of 0.55 (95% CI, 0.18 to 0.92, P = .004). The reduction among children with severe asthma was approximately 3 times greater (1.54 d/2 wk). More children in the control group (18.9%) were hospitalized during the intervention compared with children in the intervention group (14.8%), a decrease of 4.19% (CI, -8.75 to 0.36, P = .071). These improvements were maintained in the intervention group during the second year of follow-up, during which they did not have access to the asthma counselor. Conclusions: We demonstrated that an individually tailored, multifaceted intervention carried out by Masters-level social workers trained in asthma management can reduce asthma symptoms among children in the inner city.
UR - http://www.scopus.com/inward/record.url?scp=0033510680&partnerID=8YFLogxK
U2 - 10.1016/S0022-3476(99)70130-7
DO - 10.1016/S0022-3476(99)70130-7
M3 - Article
C2 - 10484799
AN - SCOPUS:0033510680
SN - 0022-3476
VL - 135
SP - 332
EP - 338
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 3
ER -