Abstract

To identify preoperative predictors for the use of any blood component during and after orthotopic liver transplantation (OLT), we performed a retrospective analysis on 602 OLT patients who were randomly split into a training set (n=482) and a validation set (n=120). Hemoglobin and calculated MELD score were identified as independent predictors for blood use using bootstrap aggregation. A logistic regression model constructed using both variables showed comparable performance in the training and validation sets. Predictive scores can be obtained from a nomogram, and a score above -2.328 predicted transfusion of any blood component with a positive predictive value of 97% and 96% in the training and validation sets, respectively.

Original languageEnglish
Pages (from-to)386-392
Number of pages7
JournalTransfusion and Apheresis Science
Volume53
Issue number3
DOIs
StatePublished - Dec 1 2015

Keywords

  • Blood transfusion
  • Hemoglobin
  • International normalized ratio (INR)
  • Model for End-Stage Liver Disease (MELD) score
  • Orthotopic liver transplantation

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