Abstract
To identify preoperative predictors for the use of any blood component during and after orthotopic liver transplantation (OLT), we performed a retrospective analysis on 602 OLT patients who were randomly split into a training set (n=482) and a validation set (n=120). Hemoglobin and calculated MELD score were identified as independent predictors for blood use using bootstrap aggregation. A logistic regression model constructed using both variables showed comparable performance in the training and validation sets. Predictive scores can be obtained from a nomogram, and a score above -2.328 predicted transfusion of any blood component with a positive predictive value of 97% and 96% in the training and validation sets, respectively.
Original language | English |
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Pages (from-to) | 386-392 |
Number of pages | 7 |
Journal | Transfusion and Apheresis Science |
Volume | 53 |
Issue number | 3 |
DOIs | |
State | Published - Dec 1 2015 |
Keywords
- Blood transfusion
- Hemoglobin
- International normalized ratio (INR)
- Model for End-Stage Liver Disease (MELD) score
- Orthotopic liver transplantation