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A quantitative model of glucose signaling in yeast reveals an incoherent feed forward loop leading to a specific, transient pulse of transcription
Sooraj Kuttykrishnan
, Jeffrey Sabina
, Laura L. Langton
, Mark Johnston
,
Michael R. Brent
Department of Computer Science & Engineering
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Computational and Systems Biology
DBBS - Human and Statistical Genetics
DBBS - Molecular Genetics and Genomics
Edison Family Center for Genome Sciences & Systems Biology
Research output
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Contribution to journal
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Article
›
peer-review
33
Scopus citations
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Dive into the research topics of 'A quantitative model of glucose signaling in yeast reveals an incoherent feed forward loop leading to a specific, transient pulse of transcription'. Together they form a unique fingerprint.
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Keyphrases
Complex Networks
100%
Gene Regulatory Network
100%
Kinetic Model
100%
Quantitative Model
100%
Transient Pulse
100%
Glucose Signaling
100%
Mig2
100%
Rgt1
100%
Incoherent Feedforward Loop
100%
Gene Expression
50%
Transcriptional Repressor
50%
Glucose Transporter 1 (GLUT1)
50%
Genetic Approach
50%
Saccharomyces Cerevisiae
50%
Feed-forward Loop
50%
Biological Components
50%
Network Components
50%
Mechanistic Explanation
50%
Kinetic Response
50%
Regulatory Loop
50%
Combining Models
50%
Biochemistry, Genetics and Molecular Biology
Pulse Rate
100%
Transcription
100%
Regulatory Network
66%
Saccharomyces cerevisiae
33%
Transcriptional Repressor
33%
Genetic Approach
33%
Glucose Transporter
33%