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A quantitative metric of pioneer activity reveals that HNF4A has stronger in vivo pioneer activity than FOXA1
Jeffrey L. Hansen,
Barak A. Cohen
Department of Genetics
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Computational and Systems Biology
DBBS - Molecular Genetics and Genomics
Institute of Clinical and Translational Sciences (ICTS)
Edison Family Center for Genome Sciences & Systems Biology
Siteman Cancer Center
COVID-19 Researchers
Research output
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Contribution to journal
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Article
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peer-review
11
Scopus citations
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Dive into the research topics of 'A quantitative metric of pioneer activity reveals that HNF4A has stronger in vivo pioneer activity than FOXA1'. Together they form a unique fingerprint.
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Keyphrases
Transcription Factor
100%
Hepatocyte nuclear Factor 4α (HNF4α)
100%
Forkhead Box A1 (FOXA1)
100%
Quantitative Metrics
100%
Pioneer Activity
100%
Binding Mode
25%
Binding Affinity
25%
Relative Difference
25%
Binding Site
12%
Doxycycline-inducible
12%
Doxycycline
12%
High Affinity
12%
Occupancy
12%
Genomic Loci
12%
Relative Binding Affinity
12%
Cooperative Mode
12%
ATAC-seq
12%
Pioneer Transcription Factor
12%
Reasonable Measures
12%
Qualitative Traits
12%
Inducible Transcription Factor
12%
Biochemistry, Genetics and Molecular Biology
Transcription Factors
100%
FOXA1
100%
Binding Affinity
30%
Binding Site
10%
Quantitative Technique
10%
ATAC-Seq
10%