@article{05e3088610bc4a95b9af7ba0857bff5f,
title = "A quantitative genomics map of rice provides genetic insights and guides breeding",
abstract = "Extensive allelic variation in agronomically important genes serves as the basis of rice breeding. Here, we present a comprehensive map of rice quantitative trait nucleotides (QTNs) and inferred QTN effects based on eight genome-wide association study cohorts. Population genetic analyses revealed that domestication, local adaptation and heterosis are all associated with QTN allele frequency changes. A genome navigation system, RiceNavi, was developed for QTN pyramiding and breeding route optimization, and implemented in the improvement of a widely cultivated indica variety. This work presents an efficient platform that bridges ever-increasing genomic knowledge and diverse improvement needs in rice.",
author = "Xin Wei and Jie Qiu and Kaicheng Yong and Jiongjiong Fan and Qi Zhang and Hua Hua and Jie Liu and Qin Wang and Olsen, {Kenneth M.} and Bin Han and Xuehui Huang",
note = "Funding Information: We are grateful to the China National Rice Research Institute, Institute of Crop Sciences of Chinese Academy of Agricultural Sciences, Institute of Plant Protection of Chinese Academy of Agricultural Sciences, Chinese Academy of Sciences Center for Excellence of Molecular Plant Sciences and Huazhong Agricultural University for providing valuable rice varieties (see Supplementary Dataset 2 for details). We thank P. Xu and J. Murray for their advice and assistance in the paper writing. This work was funded by the National Natural Science Foundation of China (grant nos. 91935301 and 31825015), Innovation Program of Shanghai Municipal Education Commission (grant no. 2017-01-07-00-02-E00039) and Program of Shanghai Academic Research Leader (grant no. 18XD1402900) to X.H. and the US National Science Foundation (Plant Genome Research Program, IOS-1947609) to K.M.O. Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Nature America, Inc.",
year = "2021",
month = feb,
doi = "10.1038/s41588-020-00769-9",
language = "English",
volume = "53",
pages = "243--253",
journal = "Nature Genetics",
issn = "1061-4036",
number = "2",
}