A Public Confession: The Retina Trumpets Its Failed Predictions

To compensate for delays of phototransduction, the retina anticipates the future by extrapolating the position of a moving object. But what if the object's motion changes, and the extrapolation is wrong? In this issue of Neuron, Schwartz and colleagues show that these prediction failures trigger a large burst of firing that helps to rapidly correct the neural representation of the object's new position.