A prototype device for non-invasive continuous monitoring of intracerebral hemorrhage

Joseph J. Korfhagen, Madhuvanthi A. Kandadai, Joseph F. Clark, Opeolu Adeoye, George J. Shaw

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

A prototype for a non-invasive, real-time, monitoring device was developed to detect changes in the brain secondary to disease or injury such as intracerebral hemorrhage (ICH). The eventual goal is a non-invasive, real time sensor that can alert the clinician to alterations in the comatose patient's brain resulting from hemorrhage, seizure or stroke. In this work, a 400MHz electromagnetic (EM) signal was transmitted with an antenna (T), incident on a 'brain gel' in vitro ICH model, and received by a receiving (R) antenna. Changes in the received signal were found to be induced by the presence of blood. The received power (PR) was found to be a linear function of the cross sectional area of blood, as measured normal to the incident wave. In addition, the sensor was able to detect as little as 1mL of blood in this 1000mL in vitro model.

Original languageEnglish
Pages (from-to)132-137
Number of pages6
JournalJournal of Neuroscience Methods
Volume213
Issue number1
DOIs
StatePublished - Feb 15 2013

Keywords

  • Brain monitoring
  • Hematoma expansion
  • Intra-cerebral hemorrhage
  • Microwave tomography
  • Stroke

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