TY - JOUR
T1 - A Proposal for the Comprehensive Care of Men on Androgen Deprivation Therapy
T2 - Recommendations from the Multidisciplinary Prostate Cancer 360 Working Group
AU - Crawford, E. David
AU - Garnick, Marc B.
AU - Eckel, Robert H.
AU - Miner, Martin M.
AU - Freedland, Stephen J.
AU - Pachynski, Russell K.
AU - Wassersug, Richard J.
AU - Rosenberg, Matthew T.
AU - Walker, Lauren M.
AU - Fairman, Ciaran
AU - Curley, Tracy
AU - Crosby, Michael
AU - Lin, Pao Hwa
AU - Hafron, Jason M.
N1 - Publisher Copyright:
© 2024 Lippincott Williams and Wilkins. All rights reserved.
PY - 2024/1/1
Y1 - 2024/1/1
N2 - Introduction:To promote comprehensive care of patients throughout the androgen deprivation therapy (ADT) prescribing process, the Prostate Cancer 360 (PC360) Working Group developed monitoring and management recommendations intended to mitigate or prevent ADT-Associated adverse events.Methods:The PC360 Working Group included 14 interdisciplinary experts with a dedicated clinical interest in prostate cancer and ADT management. The working group defined challenges associated with ADT adverse event management and then collaboratively developed comprehensive care recommendations intended to be practical for ADT prescribers.Results:The PC360 Working Group developed both overarching recommendations for ADT adverse event management and specific recommendations across 5 domains (cardiometabolic, bone, sexual, psychological, and lifestyle). The working group recommends an interdisciplinary, team-based approach wherein the ADT prescriber retains an oversight role for ADT management while empowering patients and their primary and specialty care providers to manage risk factors. The PC360 recommendations also emphasize the importance of proactive patient education that involves partners or other support providers. Recommended monitoring and assessment tools, risk factor management, and patient counseling points are also included for the 5 identified domains, with an emphasis on lifestyle and behavioral interventions that can improve quality of life and reduce the risk for ADT-Associated complications.Conclusions:Comprehensive care of patients receiving ADT requires early and ongoing coordinated management of a variety of health domains, including cardiometabolic, bone, sexual, psychological health. Patient education and primary care provider involvement should begin prior to ADT initiation and continue throughout treatment to improve patient and partner quality of life.
AB - Introduction:To promote comprehensive care of patients throughout the androgen deprivation therapy (ADT) prescribing process, the Prostate Cancer 360 (PC360) Working Group developed monitoring and management recommendations intended to mitigate or prevent ADT-Associated adverse events.Methods:The PC360 Working Group included 14 interdisciplinary experts with a dedicated clinical interest in prostate cancer and ADT management. The working group defined challenges associated with ADT adverse event management and then collaboratively developed comprehensive care recommendations intended to be practical for ADT prescribers.Results:The PC360 Working Group developed both overarching recommendations for ADT adverse event management and specific recommendations across 5 domains (cardiometabolic, bone, sexual, psychological, and lifestyle). The working group recommends an interdisciplinary, team-based approach wherein the ADT prescriber retains an oversight role for ADT management while empowering patients and their primary and specialty care providers to manage risk factors. The PC360 recommendations also emphasize the importance of proactive patient education that involves partners or other support providers. Recommended monitoring and assessment tools, risk factor management, and patient counseling points are also included for the 5 identified domains, with an emphasis on lifestyle and behavioral interventions that can improve quality of life and reduce the risk for ADT-Associated complications.Conclusions:Comprehensive care of patients receiving ADT requires early and ongoing coordinated management of a variety of health domains, including cardiometabolic, bone, sexual, psychological health. Patient education and primary care provider involvement should begin prior to ADT initiation and continue throughout treatment to improve patient and partner quality of life.
KW - adverse effects
KW - hormonal therapy
KW - lifestyle risk reduction
KW - prostatic neoplasms
KW - quality of life
UR - http://www.scopus.com/inward/record.url?scp=85181806550&partnerID=8YFLogxK
U2 - 10.1097/UPJ.0000000000000473
DO - 10.1097/UPJ.0000000000000473
M3 - Article
C2 - 37917591
AN - SCOPUS:85181806550
SN - 2352-0779
VL - 11
SP - 18
EP - 29
JO - Urology Practice
JF - Urology Practice
IS - 1
ER -