Abstract
The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the selection of clones for sequencing and for the accurate assembly of the genome sequence. Here we report the construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions. We also describe the integration of sequence data with the map.
Original language | English |
---|---|
Pages (from-to) | 934-941 |
Number of pages | 8 |
Journal | Nature |
Volume | 409 |
Issue number | 6822 |
DOIs | |
State | Published - Feb 15 2001 |
Fingerprint
Dive into the research topics of 'A physical map of the human genome'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver
}
A physical map of the human genome. / McPherson, John D.; Marra, Marco; Hillier, La Deana; Waterston, Robert H.; Chinwalla, Asif; Wallis, John; Sekhon, Mandeep; Wylie, Kristine; Mardis, Elaine R.; Wilson, Richard K.; Fulton, Robert; Kucaba, Tamara A.; Wagner-McPherson, Caryn; Barbazuk, William B.; Gregory, Simon G.; Humphray, Sean J.; French, Lisa; Evans, Richard S.; Bethel, Graeme; Whittaker, Adam; Holden, Jane L.; McCann, Owen T.; Dunham, Andrew; Soderlund, Carol; Scott, Carol E.; Bentley, David R.; Schuler, Gregory; Chen, Hsiu Chuan; Jang, Wonhee; Green, Eric D.; Idol, Jacquelyn R.; Maduro, Valerie V.Braden; Montgomery, Kate T.; Lee, Eunice; Miller, Ashley; Emerling, Suzanne; Kucherlapati, Raju; Gibbs, Richard; Scherer, Steve; Gorrell, J. Harley; Sodergren, Erica; Clerc-Blankenburg, Kerstin; Tabor, Paul; Naylor, Susan; Garcia, Dawn; de Jong, J.; Catanese, Joseph J.; Nowak, Norma; Osoegawa, Kazutoyo; Qin, Shizhen; Rowen, Lee; Madan, Anuradha; Dors, Monica; Hood, Leroy; Trask, Barbara; Friedman, Cynthia; Massa, Hillary; Cheung, Vivian G.; Kirsch, Ilan R.; Reid, Thomas; Yonescu, Raluca; Weissenbach, Jean; Bruls, Thomas; Heilig, Roland; Branscomb, Elbert; Olsen, Anne; Doggett, Norman; Cheng, Jan Fang; Hawkins, Trevor; Myers, Richard M.; Shang, Jin; Ramirez, Lucia; Schmutz, Jeremy; Velasquez, Olivia; Dixon, Kami; Stone, Nancy E.; Cox, David R.; Haussler, David; Kent, W. James; Furey, Terrence; Rogic, Sanja; Kennedy, Scot; Jones, Steven; Rosenthal, André; Wen, Gaiping; Schilhabel, Markus; Gloeckner, Gernot; Nyakatura, Gerald; Siebert, Reiner; Schlegelberger, Brigitte; Korenberg, Julie; Chen, Xiao Ning; Fujiyama, Asao; Hattori, Masahira; Toyoda, Atsushi; Yada, Tetsushi; Park, Hong Seok; Sakaki, Yoshiyuki; Shimizu, Nobuyoshi; Asakawa, Shuichi; Kawasaki, Kazuhiko; Sasaki, Takashi; Shintani, Ai; Shimizu, Atsushi; Shibuya, Kazunori; Kudoh, Jun; Minoshima, Shinsei; Ramser, Juliane; Seranski, Peter; Hoff, Celine; Poustka, Annemarie; Reinhardt, Richard; Lehrach, Hans.
In: Nature, Vol. 409, No. 6822, 15.02.2001, p. 934-941.Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - A physical map of the human genome
AU - McPherson, John D.
AU - Marra, Marco
AU - Hillier, La Deana
AU - Waterston, Robert H.
AU - Chinwalla, Asif
AU - Wallis, John
AU - Sekhon, Mandeep
AU - Wylie, Kristine
AU - Mardis, Elaine R.
AU - Wilson, Richard K.
AU - Fulton, Robert
AU - Kucaba, Tamara A.
AU - Wagner-McPherson, Caryn
AU - Barbazuk, William B.
AU - Gregory, Simon G.
AU - Humphray, Sean J.
AU - French, Lisa
AU - Evans, Richard S.
AU - Bethel, Graeme
AU - Whittaker, Adam
AU - Holden, Jane L.
AU - McCann, Owen T.
AU - Dunham, Andrew
AU - Soderlund, Carol
AU - Scott, Carol E.
AU - Bentley, David R.
AU - Schuler, Gregory
AU - Chen, Hsiu Chuan
AU - Jang, Wonhee
AU - Green, Eric D.
AU - Idol, Jacquelyn R.
AU - Maduro, Valerie V.Braden
AU - Montgomery, Kate T.
AU - Lee, Eunice
AU - Miller, Ashley
AU - Emerling, Suzanne
AU - Kucherlapati, Raju
AU - Gibbs, Richard
AU - Scherer, Steve
AU - Gorrell, J. Harley
AU - Sodergren, Erica
AU - Clerc-Blankenburg, Kerstin
AU - Tabor, Paul
AU - Naylor, Susan
AU - Garcia, Dawn
AU - de Jong, J.
AU - Catanese, Joseph J.
AU - Nowak, Norma
AU - Osoegawa, Kazutoyo
AU - Qin, Shizhen
AU - Rowen, Lee
AU - Madan, Anuradha
AU - Dors, Monica
AU - Hood, Leroy
AU - Trask, Barbara
AU - Friedman, Cynthia
AU - Massa, Hillary
AU - Cheung, Vivian G.
AU - Kirsch, Ilan R.
AU - Reid, Thomas
AU - Yonescu, Raluca
AU - Weissenbach, Jean
AU - Bruls, Thomas
AU - Heilig, Roland
AU - Branscomb, Elbert
AU - Olsen, Anne
AU - Doggett, Norman
AU - Cheng, Jan Fang
AU - Hawkins, Trevor
AU - Myers, Richard M.
AU - Shang, Jin
AU - Ramirez, Lucia
AU - Schmutz, Jeremy
AU - Velasquez, Olivia
AU - Dixon, Kami
AU - Stone, Nancy E.
AU - Cox, David R.
AU - Haussler, David
AU - Kent, W. James
AU - Furey, Terrence
AU - Rogic, Sanja
AU - Kennedy, Scot
AU - Jones, Steven
AU - Rosenthal, André
AU - Wen, Gaiping
AU - Schilhabel, Markus
AU - Gloeckner, Gernot
AU - Nyakatura, Gerald
AU - Siebert, Reiner
AU - Schlegelberger, Brigitte
AU - Korenberg, Julie
AU - Chen, Xiao Ning
AU - Fujiyama, Asao
AU - Hattori, Masahira
AU - Toyoda, Atsushi
AU - Yada, Tetsushi
AU - Park, Hong Seok
AU - Sakaki, Yoshiyuki
AU - Shimizu, Nobuyoshi
AU - Asakawa, Shuichi
AU - Kawasaki, Kazuhiko
AU - Sasaki, Takashi
AU - Shintani, Ai
AU - Shimizu, Atsushi
AU - Shibuya, Kazunori
AU - Kudoh, Jun
AU - Minoshima, Shinsei
AU - Ramser, Juliane
AU - Seranski, Peter
AU - Hoff, Celine
AU - Poustka, Annemarie
AU - Reinhardt, Richard
AU - Lehrach, Hans
PY - 2001/2/15
Y1 - 2001/2/15
N2 - The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the selection of clones for sequencing and for the accurate assembly of the genome sequence. Here we report the construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions. We also describe the integration of sequence data with the map.
AB - The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the selection of clones for sequencing and for the accurate assembly of the genome sequence. Here we report the construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions. We also describe the integration of sequence data with the map.
UR - http://www.scopus.com/inward/record.url?scp=0035865087&partnerID=8YFLogxK
U2 - 10.1038/35057157
DO - 10.1038/35057157
M3 - Article
C2 - 11237014
AN - SCOPUS:0035865087
VL - 409
SP - 934
EP - 941
JO - Nature
JF - Nature
SN - 0028-0836
IS - 6822
ER -