A Phase I Dose-Escalation and Pharmacokinetic Study of Brostallicin (PNU-166196A), A Novel DNA Minor Groove Binder, in Adult Patients with Advanced Solid Tumors

A. Craig Lockhart, Martin Howard, Kenneth R. Hande, Bruce J. Roth, Jordan D. Berlin, Franzanne Vreeland, Angela Campbell, Erminia Fontana, Francesca Fiorentini, Camilla Fowst, Victoria A. Paty, Odessa Lankford, Mace L. Rothenberg

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Pharmacology, Toxicology and Pharmaceutical Science