A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease

Alireza Faridar; Abdulmunaim M. Eid; Aaron D. Thome; Weihua Zhao; David R. Beers; Maria B. Pascual; Mohammad O. Nakawah; Gustavo C. Roman; Charles S. Davis; Michael Grundman; Joseph C. Masdeu; Stanley H. Appel

doi:10.1186/s40035-023-00387-5

A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease

Alireza Faridar
, Abdulmunaim M. Eid
, Aaron D. Thome
, Weihua Zhao
, David R. Beers
, Maria B. Pascual
, Mohammad O. Nakawah
, Gustavo C. Roman
, Charles S. Davis
, Michael Grundman
, Joseph C. Masdeu
, Stanley H. Appel

Section of Movement Disorders

Research output: Contribution to journal › Letter › peer-review

17 Scopus citations

Abstract

Trial registration : ClinicalTrials.gov Identifier: NCT05821153, Registered April 20 2023, Retrospectively registered, https://classic.clinicaltrials.gov/ct2/show/NCT05821153.

Original language	English
Article number	54
Journal	Translational Neurodegeneration
Volume	12
Issue number	1
DOIs	https://doi.org/10.1186/s40035-023-00387-5
State	Published - Dec 2023

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Faridar, A., Eid, A. M., Thome, A. D., Zhao, W., Beers, D. R., Pascual, M. B., Nakawah, M. O., Roman, G. C., Davis, C. S., Grundman, M., Masdeu, J. C., & Appel, S. H. (2023). A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease. Translational Neurodegeneration, 12(1), Article 54. https://doi.org/10.1186/s40035-023-00387-5

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title = "A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer{\textquoteright}s disease",

abstract = "Trial registration : ClinicalTrials.gov Identifier: NCT05821153, Registered April 20 2023, Retrospectively registered, https://classic.clinicaltrials.gov/ct2/show/NCT05821153.",

author = "Alireza Faridar and Eid, \{Abdulmunaim M.\} and Thome, \{Aaron D.\} and Weihua Zhao and Beers, \{David R.\} and Pascual, \{Maria B.\} and Nakawah, \{Mohammad O.\} and Roman, \{Gustavo C.\} and Davis, \{Charles S.\} and Michael Grundman and Masdeu, \{Joseph C.\} and Appel, \{Stanley H.\}",

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year = "2023",

month = dec,

doi = "10.1186/s40035-023-00387-5",

language = "English",

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T1 - A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease

AU - Faridar, Alireza

AU - Eid, Abdulmunaim M.

AU - Thome, Aaron D.

AU - Zhao, Weihua

AU - Beers, David R.

AU - Pascual, Maria B.

AU - Nakawah, Mohammad O.

AU - Roman, Gustavo C.

AU - Davis, Charles S.

AU - Grundman, Michael

AU - Masdeu, Joseph C.

AU - Appel, Stanley H.

PY - 2023/12

Y1 - 2023/12

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AB - Trial registration : ClinicalTrials.gov Identifier: NCT05821153, Registered April 20 2023, Retrospectively registered, https://classic.clinicaltrials.gov/ct2/show/NCT05821153.

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U2 - 10.1186/s40035-023-00387-5

DO - 10.1186/s40035-023-00387-5

M3 - Letter

AN - SCOPUS:85176461023

SN - 2047-9158

VL - 12

JO - Translational Neurodegeneration

JF - Translational Neurodegeneration

IS - 1

M1 - 54

ER -

A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease

Abstract

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