TY - JOUR
T1 - A novel system dynamics model of female obesity and fertility
AU - Sabounchi, Nasim S.
AU - Hovmand, Peter S.
AU - Osgood, Nathaniel D.
AU - Dyck, Roland F.
AU - Jungheim, Emily S.
PY - 2014/7
Y1 - 2014/7
N2 - Objectives. Our objective was to create a system dynamics model specific to weight gain and obesity in women of reproductive age that could inform future health policies and have the potential for use in preconception interventions targeting obese women. Methods. We used our system dynamics model of obesity in women to test various strategies for family building, including ovulation induction versus weight loss to improve ovulation. Outcomes included relative fecundability, postpartum body mass index, and mortality. Results. Our system dynamics model demonstrated that obese women who become pregnant exhibit increasing obesity levels over time with elevated morbidity and mortality. Alternatively, obese women who lose weight prior to pregnancy have improved reproductive outcomes but may risk an age-related decline in fertility, which can affect overall family size. Conclusions. Our model highlights important public health issues regarding obesity in women of reproductive age. The model may be useful in preconception counseling of obese women who are attempting to balance the competing risks associated with age-related declines in fertility and clinically meaningful weight loss.
AB - Objectives. Our objective was to create a system dynamics model specific to weight gain and obesity in women of reproductive age that could inform future health policies and have the potential for use in preconception interventions targeting obese women. Methods. We used our system dynamics model of obesity in women to test various strategies for family building, including ovulation induction versus weight loss to improve ovulation. Outcomes included relative fecundability, postpartum body mass index, and mortality. Results. Our system dynamics model demonstrated that obese women who become pregnant exhibit increasing obesity levels over time with elevated morbidity and mortality. Alternatively, obese women who lose weight prior to pregnancy have improved reproductive outcomes but may risk an age-related decline in fertility, which can affect overall family size. Conclusions. Our model highlights important public health issues regarding obesity in women of reproductive age. The model may be useful in preconception counseling of obese women who are attempting to balance the competing risks associated with age-related declines in fertility and clinically meaningful weight loss.
UR - http://www.scopus.com/inward/record.url?scp=84902665551&partnerID=8YFLogxK
U2 - 10.2105/AJPH.2014.301898
DO - 10.2105/AJPH.2014.301898
M3 - Article
C2 - 24832413
AN - SCOPUS:84902665551
SN - 0090-0036
VL - 104
SP - 1240
EP - 1246
JO - American Journal of Public Health
JF - American Journal of Public Health
IS - 7
ER -