TY - JOUR
T1 - A novel secretion apparatus for the assembly of adhesive bacterial pili
AU - Jacob-Dubuisson, Françoise
AU - Kuehn, Meta
AU - Hultgren, Scott J.
N1 - Funding Information:
We thank Hal Jones for communicating some unpublished data, and Karen Dodson for critical reading of the manuscript. F.J-D. is the recipient of a Long Term Post Doctoral EMBO Fellowshipa nd M.K. receiveds upport from NIH Training Grant AI07172. Work in this lab was supported by grants to S.J.H. from L.P. Markey Charitable Trust, Washington University/Monsanto Biomedical Research Contract, National Institutes of Health (Support Grant 1ROIAI29549), Institutional Biomedical Research (Support Grant 2-SO7-RR-5389) and the American Cancer Society( Grant IN-36).
PY - 1993/5
Y1 - 1993/5
N2 - The biogenesis of most types of bacterial pili requires two specialized proteins: a chaperone that caps the pilus subunits in the periplasm, and an outer membrane usher that receives the subunits and serves as an assembly platform. This secretion and assembly machinery is proposed to be a novel export apparatus found widely in Gram-negative pathogens.
AB - The biogenesis of most types of bacterial pili requires two specialized proteins: a chaperone that caps the pilus subunits in the periplasm, and an outer membrane usher that receives the subunits and serves as an assembly platform. This secretion and assembly machinery is proposed to be a novel export apparatus found widely in Gram-negative pathogens.
UR - http://www.scopus.com/inward/record.url?scp=0027286567&partnerID=8YFLogxK
U2 - 10.1016/0966-842X(93)90032-M
DO - 10.1016/0966-842X(93)90032-M
M3 - Review article
C2 - 7913856
AN - SCOPUS:0027286567
SN - 0966-842X
VL - 1
SP - 50
EP - 55
JO - Trends in Microbiology
JF - Trends in Microbiology
IS - 2
ER -