A novel approach to phylogenetic tree construction using stochastic optimization and clustering

  • Ling Qin
  • , Yixin Chen
  • , Yi Pan
  • , Ling Chen

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational biology. Results: A new phylogenetic tree construction method from a given set of objects (proteins, species, etc.) is presented. As an extension of ant colony optimization, this method proposes an adaptive phylogenetic clustering algorithm based on a digraph to find a tree structure that defines the ancestral relationships among the given objects. Conclusion: Our phylogenetic tree construction method is tested to compare its results with that of the genetic algorithm (GA). Experimental results show that our algorithm converges much faster and also achieves higher quality than GA.

Original languageEnglish
Article numberS24
JournalBMC bioinformatics
Volume7
Issue numberSUPPL.4
DOIs
StatePublished - Dec 12 2006

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