TY - JOUR
T1 - A novel ant colony optimization based algorithm for identifying gene regulatory elements
AU - Liu, Wei
AU - Chen, Hanwu
AU - Chen, Ling
AU - Chen, Yixin
PY - 2013
Y1 - 2013
N2 - It is one of the most important tasks in bioinformatics to identify the regulatory elements in gene sequences. Most of the current algorithms for identifying regulatory elements are easily to converge into a local optimum, and have high time complexity. Therefore, we propose a novel optimization algorithm named ACRI(antcolony- regulatory-identification) for identifying regulatory elements. Based on powerful optimization ability of antcolony algorithm, the algorithm ACRI can not only improve the quality of results, but also solve the problem at a very high speed. Experimental results show that ACRI can obtain higher quality of solutions using less computational time than other traditional algorithms.
AB - It is one of the most important tasks in bioinformatics to identify the regulatory elements in gene sequences. Most of the current algorithms for identifying regulatory elements are easily to converge into a local optimum, and have high time complexity. Therefore, we propose a novel optimization algorithm named ACRI(antcolony- regulatory-identification) for identifying regulatory elements. Based on powerful optimization ability of antcolony algorithm, the algorithm ACRI can not only improve the quality of results, but also solve the problem at a very high speed. Experimental results show that ACRI can obtain higher quality of solutions using less computational time than other traditional algorithms.
KW - Ant colony optimization
KW - Bioinformatics
KW - Gene regulatory elements
UR - https://www.scopus.com/pages/publications/84875140782
U2 - 10.4304/jcp.8.3.613-621
DO - 10.4304/jcp.8.3.613-621
M3 - Article
AN - SCOPUS:84875140782
SN - 1796-203X
VL - 8
SP - 613
EP - 621
JO - Journal of Computers (Finland)
JF - Journal of Computers (Finland)
IS - 3
ER -