A new nucleoside analogue with potent activity against mutant sr39 Herpes Simplex Virus-1 (HSV-1) Thymidine Kinase (TK)

Keyphrases

• Acyclovir 33%
• Amino Acid Residues 33%
• Binding Site 33%
• Cytotoxic Activity 33%
• Docking Studies 33%
• Flexible Side Chains 33%
• Fluorinated nucleosides 33%
• Fluoro 33%
• Ganciclovir 33%
• HeLa Cells 33%
• Herpes Simplex Virus Type 1 (HSV-1) 100%
• Ligand Docking 33%
• Nucleoside Analogues 100%
• Penciclovir 33%
• Positron Emission Tomography Scanner 33%
• Reporter Gene Expression 33%
• Selective Activity 33%
• Thymidine Kinase 100%

Medicine and Dentistry

• Aciclovir 33%
• Amino Acid 33%
• Antiviral Drug 33%
• Binding Site 33%
• Cytotoxicity 33%
• Fluorine-18 100%
• Ganciclovir 33%
• Gene Expression 33%
• Human Alphaherpesvirus 1 100%
• Nucleoside Analog 100%
• Penciclovir 33%
• Positron Emission Tomography 33%
• Reporter Gene 33%
• Thymidine Kinase 100%

Pharmacology, Toxicology and Pharmaceutical Science

• Aciclovir 33%
• Amino Acid 33%
• Antiviral Drug 33%
• Binding Site 33%
• Cytotoxicity 33%
• Fluorine 18 100%
• Ganciclovir 33%
• Human Alphaherpesvirus 1 100%
• Nucleoside Analog 100%
• Penciclovir 33%
• Thymidine Kinase 100%