@article{24a8df90c8394945907cef9186afa3a7,
title = "A new ATP-independent DNA endonuclease from Schizosaccharomyces pombe that recognizes cyclobutane pyrimidine dimers and 6-4 photoproducts",
abstract = "We have discovered a new DNA endonuclease in the fission yeast Schizosaccharomyces pombe which recognizes cyclobutane pyrimidine dimers and (6-4) pyrimidine-pyrimidone photoproducts. S.pombe DNA endonuclease (SPDE) catalyzes a single ATPindependent incision immediately 5′ to the UV photoproduct and generates termini containing 3′ hydroxyl and 5′ phosphoryl groups. Based on these properties, we propose that SPDE may function in a DNA repair capacity, representing the initial recognition/ cleavage step of a DNA excision repair pathway.",
author = "Bowman, \{Krista K.\} and Khalifah Sidik and Smith, \{Colin A.\} and Taylor, \{John stephen\} and Doetsch, \{Paul W.\} and Freyer, \{Greg A.\}",
note = "Funding Information: We would like to thank R.S.Lloyd and A.Sancar for their gifts of T4 endonuclease V and E.coli DNA photolyase. This work has been supported by grants from NIH to P.W.D. (CA42608 and CA55896) and to J.-S.T. (CA40463) and to G.F. (CA12536) and from the American Cancer Society to P.W.D. (NP806). P.W.D. is the recipient of a Research Career Development Award from the NIH (CA 01441).",
year = "1994",
month = aug,
day = "11",
doi = "10.1093/nar/22.15.3026",
language = "English",
volume = "22",
pages = "3026--3032",
journal = "Nucleic acids research",
issn = "0305-1048",
number = "15",
}