@article{853ad5ff9c4a4325bcdda3b62ccda0f3,
title = "A Naturalistic Study of Driving Behavior in Older Adults and Preclinical Alzheimer Disease: A Pilot Study",
abstract = "A clinical consequence of symptomatic Alzheimer{\textquoteright}s disease (AD) is impaired driving performance. However, decline in driving performance may begin in the preclinical stage of AD. We used a naturalistic driving methodology to examine differences in driving behavior over one year in a small sample of cognitively normal older adults with (n = 10) and without (n = 10) preclinical AD. As expected with a small sample size, there were no statistically significant differences between the two groups, but older adults with preclinical AD drove less often, were less likely to drive at night, and had fewer aggressive behaviors such as hard braking, speeding, and sudden acceleration. The sample size required to power a larger study to determine differences was calculated.",
keywords = "Alzheimer{\textquoteright}s disease, driving, naturalistic methodology, older adults",
author = "Babulal, {Ganesh M.} and Stout, {Sarah H.} and Benzinger, {Tammie L.S.} and Ott, {Brian R.} and Carr, {David B.} and Mollie Webb and Traub, {Cindy M.} and Aaron Addison and Morris, {John C.} and Warren, {David K.} and Roe, {Catherine M.}",
note = "Funding Information: The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Funding for this study was provided by Washington University (University Research Strategic Alliance [URSA] 2016), the National Institute on Aging (R01-AG043434, R01-AG43434-03S1, P50-AG05681, P01-AG03991, P01-AG026276), Fred Simmons and Olga Mohan, the Charles and Joanne Knight Alzheimer{\textquoteright}s Research Initiative of the Washington University Knight Alzheimer{\textquoteright}s Disease Research Center, and the Washington University Institute of Clinical and Translational Sciences (UL1 TR000448 from the National Center for Advancing Translational Sciences [NCATS]). Imaging facilities were supported by the Washington University Institute of Clinical and Translational Sciences (UL1 TR000448 from the NCATS of the National Institutes of Health [NIH]). Imaging analyses used the services of the Neuroimaging Informatics and Analysis Center, supported by the NIH (5P30NS048056). Publisher Copyright: {\textcopyright} The Author(s) 2017.",
year = "2019",
month = feb,
day = "1",
doi = "10.1177/0733464817690679",
language = "English",
volume = "38",
pages = "277--289",
journal = "Journal of Applied Gerontology",
issn = "0733-4648",
number = "2",
}