A multi-shank silk-backed parylene neural probe for reliable chronic recording

  • Fan Wu
  • , Lee Tien
  • , Fujun Chen
  • , David Kaplan
  • , Joshua Berke
  • , Euisik Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Many chronic brain implants would benefit from a neural probe with many densely configured electrodes with stable recording quality. We present a novel strategy to scale up the number of electrodes with minimized risk of proportionally increasing the adverse foreign body reactions. A flexible parylene probe having 64 electrodes has been designed and fabricated with unique geometries for reduced tissue reactions. Biocompatible silk fibroin was patterned to provide a biodegradable mechanical support of the flexible probe during insertion. We validated the design with in vivo recording in rats and observed no significant deterioration in recording quality for over 5 weeks.

Original languageEnglish
Title of host publication2013 Transducers and Eurosensors XXVII
Subtitle of host publicationThe 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Pages888-891
Number of pages4
DOIs
StatePublished - 2013
Event2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, Spain
Duration: Jun 16 2013Jun 20 2013

Publication series

Name2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Conference

Conference2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Country/TerritorySpain
CityBarcelona
Period06/16/1306/20/13

Keywords

  • Biocompatibility
  • Neural Probe
  • Parylene
  • Silk Fibroin

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