TY - JOUR
T1 - A multi-institutional report of peri-operative and functional outcomes after robot-assisted partial nephrectomy in patients with a solitary kidney
AU - Gul, Zeynep
AU - Blum, Kyle A.
AU - Paulucci, David J.
AU - Abaza, Ronney
AU - Eun, Daniel D.
AU - Bhandari, Akshay
AU - Hemal, Ashok K.
AU - Porter, James
AU - Badani, Ketan K.
N1 - Publisher Copyright:
© 2018, Springer-Verlag London Ltd., part of Springer Nature.
PY - 2019/6/1
Y1 - 2019/6/1
N2 - To evaluate peri- and post-operative outcomes after robotic partial nephrectomy (RPN) in patients with a solitary kidney. A multi-institutional database of 1868 patients was used to identify 35 patients with a solitary kidney who underwent RPN at six different centers from 2007 to 2016. Peri-operative outcomes were summarized with descriptive statistics. We assessed the change in eGFR over time with a linear mixed-effects model. Median operative time, ischemia time, and estimated blood loss were 172 min, 16 min, and 113 mL, respectively. There were no positive surgical margins. The median length of stay was 1 day (range 1–7), and over half (54.3%) of patients were discharged one post-operative day 1. Seven post-operative complications occurred in six patients (17.1%); of which four were Clavien I, two were Clavien II, and one was Clavien III. The linear decline in eGFR up to 24 month post-RPN was marginal and not significant (ß = − 0.14; 95% CI = − 0.51, 0.23; p = 0.453), with predicted mean eGFR decreasing from 59.2 to 55.8 mL/min/1.73 m2 at 24 months. These results suggest that, in patients with a solitary kidney, RPN is a safe and feasible treatment option. In patients with a solitary kidney, RPN did not significantly compromise renal function for up to 2 years after surgery.
AB - To evaluate peri- and post-operative outcomes after robotic partial nephrectomy (RPN) in patients with a solitary kidney. A multi-institutional database of 1868 patients was used to identify 35 patients with a solitary kidney who underwent RPN at six different centers from 2007 to 2016. Peri-operative outcomes were summarized with descriptive statistics. We assessed the change in eGFR over time with a linear mixed-effects model. Median operative time, ischemia time, and estimated blood loss were 172 min, 16 min, and 113 mL, respectively. There were no positive surgical margins. The median length of stay was 1 day (range 1–7), and over half (54.3%) of patients were discharged one post-operative day 1. Seven post-operative complications occurred in six patients (17.1%); of which four were Clavien I, two were Clavien II, and one was Clavien III. The linear decline in eGFR up to 24 month post-RPN was marginal and not significant (ß = − 0.14; 95% CI = − 0.51, 0.23; p = 0.453), with predicted mean eGFR decreasing from 59.2 to 55.8 mL/min/1.73 m2 at 24 months. These results suggest that, in patients with a solitary kidney, RPN is a safe and feasible treatment option. In patients with a solitary kidney, RPN did not significantly compromise renal function for up to 2 years after surgery.
KW - Glomerular filtration rate
KW - Nephron sparing surgery
KW - Partial nephrectomy
KW - Renal cancer
KW - Robotics
KW - Solitary kidney
UR - http://www.scopus.com/inward/record.url?scp=85055260857&partnerID=8YFLogxK
U2 - 10.1007/s11701-018-0883-5
DO - 10.1007/s11701-018-0883-5
M3 - Article
C2 - 30315391
AN - SCOPUS:85055260857
SN - 1863-2483
VL - 13
SP - 423
EP - 428
JO - Journal of Robotic Surgery
JF - Journal of Robotic Surgery
IS - 3
ER -