A mouse α-globin-related pseudogene lacking intervening sequences

Elio F. Vanin; Gregory I. Goldberg; Philip W. Tucker; Oliver Smithies

doi:10.1038/286222a0

A mouse α-globin-related pseudogene lacking intervening sequences

Elio F. Vanin, Gregory I. Goldberg, Philip W. Tucker, Oliver Smithies

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100 Scopus citations

Abstract

A mouse α-globin-related pseudogene (ψα30.5) completely lacks intervening sequences, and could not code for a functional globin polypeptide because of frameshifts. The widespread occurrence of globin pseudogenes in other species suggests that they are not 'dead' genes but may be important in controlling globin expression.

Original language	English
Pages (from-to)	222-226
Number of pages	5
Journal	Nature
Volume	286
Issue number	5770
DOIs	https://doi.org/10.1038/286222a0
State	Published - Dec 1 1980
Externally published	Yes

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title = "A mouse α-globin-related pseudogene lacking intervening sequences",

abstract = "A mouse α-globin-related pseudogene (ψα30.5) completely lacks intervening sequences, and could not code for a functional globin polypeptide because of frameshifts. The widespread occurrence of globin pseudogenes in other species suggests that they are not 'dead' genes but may be important in controlling globin expression.",

author = "Vanin, {Elio F.} and Goldberg, {Gregory I.} and Tucker, {Philip W.} and Oliver Smithies",

year = "1980",

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doi = "10.1038/286222a0",

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T1 - A mouse α-globin-related pseudogene lacking intervening sequences

AU - Vanin, Elio F.

AU - Goldberg, Gregory I.

AU - Tucker, Philip W.

AU - Smithies, Oliver

PY - 1980/12/1

Y1 - 1980/12/1

N2 - A mouse α-globin-related pseudogene (ψα30.5) completely lacks intervening sequences, and could not code for a functional globin polypeptide because of frameshifts. The widespread occurrence of globin pseudogenes in other species suggests that they are not 'dead' genes but may be important in controlling globin expression.

AB - A mouse α-globin-related pseudogene (ψα30.5) completely lacks intervening sequences, and could not code for a functional globin polypeptide because of frameshifts. The widespread occurrence of globin pseudogenes in other species suggests that they are not 'dead' genes but may be important in controlling globin expression.

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U2 - 10.1038/286222a0

DO - 10.1038/286222a0

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SN - 0028-0836

VL - 286

SP - 222

EP - 226

JO - Nature

JF - Nature

IS - 5770

ER -

A mouse α-globin-related pseudogene lacking intervening sequences

Abstract

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