@inproceedings{e2f7b77407ef4935804cba625c8c8de5,
title = "A monomeric water-soluble NIR-absorbing porphyrin derivative as in vivo photoacoustic tomography contrast agent",
abstract = "A PEGylated quinoline-annulated porphyrin derivative was synthesized as in vivo photoacoustic tomography contrast agent. It possesses high solubility and stability in water and phosphate-buffered saline. No toxicity sign was observed in BALB/c mice. The dye demonstrates a 4-fold higher photoacoustic signal generation efficiency compared to fresh rat blood. Injection of the dye results in a significant enhancement of in vivo PAT images of murine tumors. Analysis of the mouse urine after injection revealed an unaltered renal filtration of the contrast agent.",
keywords = "Contrast agent, In vivo photoacoustic tomography, PEG-ylation, Photoacoustic imaging, Porphyrin",
author = "Mohsen Erfanzadeh and Michael Luciano and Feifei Zhou and Christian Br{\"u}ckner and Quing Zhu",
note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; Photons Plus Ultrasound: Imaging and Sensing 2017 ; Conference date: 29-01-2017 Through 01-02-2017",
year = "2017",
doi = "10.1117/12.2249877",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Oraevsky, \{Alexander A.\} and Wang, \{Lihong V.\}",
booktitle = "Photons Plus Ultrasound",
}